Alternative approaches to control--quo vadit?

Veterinary Parasitology
Frank Jackson, Jim Miller

Abstract

The increasing prevalence of anthelmintic resistance has provided a spur for research into 'alternative/novel' approaches to the control of helminthoses that are intended to reduce our reliance upon using chemoprophylaxis. The different approaches either target the parasite population in the host or on pasture, but the goal of all of them is to restrict host parasite contact to levels which minimise the impact of helminths on host welfare and/or performance. Infrapopulation regulation can be achieved through methods that enhance immunity such as optimised nutrition (immunonutrition), genetic selection and vaccination, or by an 'anthelmintic' route using bioactive forages, copper oxide wire particles, or use of targeted selective treatment strategies such as FAMACHA, which reduce the selection pressure for the development of resistance by maintaining a population in refugia. Suprapopulation control can be achieved through grazing management, or by using predacious fungi such as Duddingtonia flagrans. All of these approaches have been developed beyond the proof of concept stage and some are capable of being employed currently. However, some still require knowledge transfer, or commercialisation before they can be tested and widel...Continue Reading

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Citations

Jun 28, 2014·Parasite : Journal De La Société Française De Parasitologie·Juan J VillalbaJohn Glendinning
Nov 23, 2013·Applied Microbiology and Biotechnology·Fabio Ribeiro Braga, Jackson Victor de Araújo
Jul 16, 2011·Journal of Ethnobiology and Ethnomedicine·Cheryl Lans, Nancy Turner
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Jul 14, 2010·Veterinary Parasitology·Alfredo Skrebsky CezarFernanda Silveira Flôres Vogel
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Apr 2, 2010·Veterinary Parasitology·Daniela Guedes da CruzClóvis de Paula Santos
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Dec 28, 2010·Veterinary Parasitology·Falko KaufmannMatthias Gauly

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Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.