PMID: 9542685May 30, 1998Paper

Alternative approaches to the management of priapism

International Journal of Impotence Research
J D deHollW D Steers

Abstract

Herein we describe the use of intracavernous methylene blue (MB), a guanylate cyclase inhibitor, or internal pudendal artery embolization for the treatment of priapism. Eleven patients with priapism were treated from 1993-1996. Etiologies of priapism included PGE1/papaverine (3), trazodone (2), and sickle cell disease (1), in the other five cases the causes the cause was unknown. The average duration of priapism was 27 h for all patients (6-72 h). Five patients who failed intracavernous MB or an alpha-adrenergic agonist, underwent unilateral or bilateral pudendal artery embolization. The average duration of priapism for patients undergoing embolization was 43 h. Sixty-seven percent of the patients treated with MB responded with immediate detumescence. One-hundred percent of patients with priapism secondary to intracavernous injection therapy or trazodone responded. Of the five patients who underwent embolization, 40% achieved immediate pain relief and subsequent detumescence. The three non-responders exhibited a partial detumescence over 47-72 h. After follow-up of one year embolization available for only two patients revealed that one regained potency while the other remained impotent. These results confirmed that MB is effect...Continue Reading

Citations

Jan 21, 2006·The Journal of Sexual Medicine·Ahmed AteyahHatem Saad El-Den
Dec 3, 2003·Expert Opinion on Pharmacotherapy·Zafar MaanHitendra R H Patel
Mar 5, 2005·International Braz J Urol : Official Journal of the Brazilian Society of Urology·C Van der HorstK P Juenemann
Aug 23, 2003·International Journal of Impotence Research·C M EarleZ S Wisniewski
Jun 26, 2002·BJU International·S R KeoghaneM A W Miller
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