Alternative to antibiotics for managing asymptomatic and non-symptomatic bacteriuria in older persons: a review

British Journal of Community Nursing
Debbie Duncan

Abstract

Recurrent urinary tract infection (UTI) is one of the most common reasons for long-term antibiotic use in frail older people, and these individuals often have non-symptomatic bacteriuria. This article reviews the literature and recommendations for the treatment of UTIs particularly in the older population (>65 years). It considers the question: is there an alternative for antibiotics for asymptomatic and non-symptomatic bacteriuria in older adults? D-mannose powder has been recommended for the treatment of UTIs, as when applied locally, it reduces the adherence of Escherichia coli. In one study, D-mannose was reviewed for the prophylaxis of recurrent UTIs in women, and the findings indicated that it may be useful for UTI prevention instead of prophylactic antibiotics. There is a lack of information about the efficacy of cranberry products combined with D-mannose in this regard, and this is an area for further research.

References

Aug 10, 2000·International Journal of Antimicrobial Agents·M D Melekos, K G Naber
Sep 2, 2000·The Journal of Antimicrobial Chemotherapy·T M Hooton
Sep 14, 2000·Age and Ageing·M E McMurdo, N D Gillespie
May 16, 2002·Molecular Microbiology·Chia-Suei HungScott J Hultgren
Jul 13, 2002·The American Journal of Medicine·Betsy Foxman
Oct 7, 2004·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·T S DimitrovR Passadilla
Jun 2, 2007·The Journal of Antimicrobial Chemotherapy·Sharon HillierStephen Palmer
Dec 5, 2008·Journal of the American Geriatrics Society·Henry J Woodford, James George
Jun 6, 2009·Journal of the American Geriatrics Society·Manisha Juthani-MehtaMary Tinetti
Dec 9, 2010·Nature Reviews. Urology·Betsy Foxman
Feb 26, 2011·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Stefano SalvatoreMarco Torella
Jul 15, 2011·Clinical Interventions in Aging·Louise A BeveridgeMarion Et McMurdo
Aug 16, 2011·The American Journal of Geriatric Pharmacotherapy·S James Matthews, Jason W Lancaster
Nov 18, 2011·Science Translational Medicine·Corinne K CusumanoScott J Hultgren
Mar 23, 2012·The Journal of Antimicrobial Chemotherapy·Pamela McCleanCarmel Hughes
May 31, 2013·BMJ : British Medical Journal·Kalpana Gupta, Barbara W Trautner
Sep 5, 2013·Proceedings of the National Academy of Sciences of the United States of America·Drew J SchwartzScott J Hultgren
Nov 13, 2013·BJU International·Silvio Altarac, Dino Papeš
Feb 4, 2014·Infectious Disease Clinics of North America·Betsy Foxman
Feb 7, 2014·Critical Reviews in Food Science and Nutrition·Salvatore MicaliMichele Navarra
Jul 6, 2014·BMJ : British Medical Journal·Sean NinanGavin Barlow
Apr 9, 2015·Nature Reviews. Microbiology·Ana L Flores-MirelesScott J Hultgren
Aug 20, 2015·Journal of Family Medicine and Primary Care·Carolin Elizabeth GeorgeTata Rao
Oct 18, 2015·The Urologic Clinics of North America·Keri DetweilerSophie G Fletcher
Jul 13, 2016·British Journal of Community Nursing·Alison While
Dec 3, 2016·Current Opinion in Urology·Tommaso CaiTruls E Bjerklund Johansen
Nov 25, 2017·BMJ : British Medical Journal·Jonathan BarclayChris Harding

❮ Previous
Next ❯

Citations

Oct 12, 2021·Journal of Dietary Supplements·Roberto CotelleseStefano Togni

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.