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Alternatively spliced isoforms reveal a novel type of PTB domain in CCM2 protein

Scientific Reports

Nov 1, 2019

Xiaoting JiangJun Xia Zhang

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Abstract

Cerebral cavernous malformations (CCMs) is a microvascular disorder in the central nervous system. Despite tremendous efforts, the causal genetic mutation in some CCM patients has not be identified, raising the possibility of an unknown CCM locus. The CCM2/MGC4607 gene has been identifi...read more

Mentioned in this Paper

Alternative Splicing
Exons
Genes
Genome
Transcription, Genetic
Promoter
Site
Microvascular Angina
Binding Protein
Cerebrocostomandibular Syndrome
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Alternatively spliced isoforms reveal a novel type of PTB domain in CCM2 protein

Scientific Reports

Nov 1, 2019

Xiaoting JiangJun Xia Zhang

PMID: 31676827

DOI: 10.1038/s41598-019-52386-0

Abstract

Cerebral cavernous malformations (CCMs) is a microvascular disorder in the central nervous system. Despite tremendous efforts, the causal genetic mutation in some CCM patients has not be identified, raising the possibility of an unknown CCM locus. The CCM2/MGC4607 gene has been identifi...read more

Mentioned in this Paper

Alternative Splicing
Exons
Genes
Genome
Transcription, Genetic

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