PMID: 11322172Apr 27, 2001Paper

Aluminium toxicokinetics: an updated minireview

Pharmacology & Toxicology
Robert A Yokel, P J McNamara

Abstract

This MiniReview updates and expands the MiniReview of aluminium toxicokinetics by Wilhelm et al. published by this journal in 1990. The use of 26Al, analyzed by accelerator mass spectrometry, now enables determination of Al toxicokinetics under physiological conditions. There is concern about aluminium in drinking water. The common sources of aluminium for man are reviewed. Oral Al bioavailability from water appears to be about 0.3%. Food is the primary common source. Al bioavailability from food has not been adequately determined. Industrial and medicinal exposure, and perhaps antiperspirant use, can significantly increase absorbed aluminium. Inhalation bioavailability of airborne soluble Al appears to be about 1.5% in the industrial environment. Al may distribute to the brain from the nasal cavity, but the significance of this exposure route is unknown. Systemic Al bioavailability after single underarm antiperspirant application may be up to 0.012%. All intramuscularly injected Al, e.g. from vaccines, may eventually be absorbed. Al distributes unequally to all tissues. Distribution and renal excretion appear to be enhanced by citrate. Brain uptake of Al may be mediated by Al transferrin and Al citrate complexes. There appears...Continue Reading

Citations

Jul 28, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Hans-Olov HellströmKarl Michaëlsson
Jul 2, 2009·Archives of Toxicology·Vijay Kumar, Kiran Dip Gill
Jul 30, 2008·Archives of Environmental Contamination and Toxicology·A HinwoodR Rogan
Oct 3, 2008·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Lei ChenMichal Toborek
Apr 29, 2010·Medical & Biological Engineering & Computing·Goran KekovicSlobodan Sekulic
Oct 6, 2007·Biological Trace Element Research·T BaydarG Sahin
May 4, 2011·Biological Trace Element Research·María del Carmen ContiniStella Mahieu
Dec 30, 2011·Biological Trace Element Research·Yue SheYanfei Li
Aug 3, 2013·Journal of Forensic and Legal Medicine·Mustafa Yildiz, Gonenc Kocabay
Oct 22, 2003·Journal of Inorganic Biochemistry·A del OlmoC SanJose
Feb 6, 2003·Drug Discovery Today·Paul Baldrick
Jul 16, 2005·Food Additives and Contaminants·Salim M Saiyed, Robert A Yokel
May 14, 2008·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·H Barton
Dec 22, 2007·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Daniel KrewskiVirginie Rondeau
Dec 15, 2010·Rejuvenation Research·Maximus V Peto
Oct 19, 2001·Toxicological Sciences : an Official Journal of the Society of Toxicology·R A YokelP J McNamara
Jul 30, 2003·Clinical Pharmacokinetics·David StepenskyAmnon Hoffman
Nov 30, 2013·Chemosphere·Yanzhu ZhuHaitao Li
Nov 28, 2014·Immunotherapy·Christopher A ShawLucija Tomljenovic
Feb 4, 2005·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Z Rengel
Nov 12, 2002·Environmental Health Perspectives·Robert A Yokel
Jun 24, 2004·Lipids in Health and Disease·Jignesh D PandyaSurendra S Katyare
Jun 28, 2005·Biochimica Et Biophysica Acta·Christopher J L Silwood, Martin Grootveld
Jun 6, 2006·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Marjorie S FriesenRobert D Gair
Sep 9, 2015·Journal of Inorganic Biochemistry·Elena FormosoXabier Lopez
Nov 22, 2011·Journal of Inorganic Biochemistry·Lucija Tomljenovic, Christopher A Shaw
Jul 21, 2010·Journal of Pharmaceutical and Biomedical Analysis·Zakelj SimonKristl Albin
Jun 18, 2010·Plant Physiology and Biochemistry : PPB·Luciane Belmonte PereiraMaria R C Schetinger
May 1, 2010·Environmental Toxicology and Pharmacology·Biao WangXin Deng
Jul 7, 2009·Chemico-biological Interactions·Bitte Aspenström-FagerlundAnders W Glynn
Nov 26, 2015·Neuroscience Letters·Zengjin WangXiulan Zhao
Apr 3, 2008·Analytical Biochemistry·Denise BohrerSolange Cristina Garcia
Aug 11, 2007·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Bimla NehruAarti Garg
Mar 23, 2007·Toxicology and Applied Pharmacology·Yongbae KimJoseph P Bressler
Sep 13, 2008·Journal of Applied Toxicology : JAT·Ferdinando MannelloPhilippa D Darbre

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Human & Experimental Toxicology
N D PriestL K Fifield
The American Journal of Medicine
Christopher Exley
Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
Elena SizovaAnatoly Skalny
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
A C KatzR I Freudenthal
© 2021 Meta ULC. All rights reserved