Abstract
Mental status changes in an immunosuppressed child can be due to a variety of causes; aluminum toxicity is rarely considered. We report a teenage girl with acute lymphoblastic leukemia who developed mental status changes, speech disturbance, coarse tremor, and abnormal EEG findings following intravesical 1% alum irrigation and administration of aluminum-containing antacids. Her serum aluminum levels were mildly elevated (14-22 milligram(s), normal 0-6 milligram(s)), and bone marrow biopsy specimens demonstrated aluminum deposition on special staining (Krueger's method). All abnormalities resolved after a nine-week course of intravenous deferoxamine.
References
Jul 1, 1992·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·A Sedman
Mar 1, 1992·The Journal of Urology·D A ShoskesR J Honey
May 1, 1991·European Journal of Pediatrics·A MorenoA Ballabriga
Oct 1, 1990·Urology·M D SeearP C Rogers
Jul 1, 1989·JPEN. Journal of Parenteral and Enteral Nutrition·M E BozynskiE J Wright
Jul 1, 1989·Lancet·P AltmannF Marsh
Sep 1, 1988·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·K B Modi, P J Paterson
Sep 1, 1986·The Journal of Urology·L R KavoussiG L Andriole
Jul 1, 1985·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·R A Clark, G L Krueger
Jun 1, 1985·The Journal of Urology·A K GoelT K Sen
Sep 27, 1980·Lancet·P AckrillK C Hodge
Apr 26, 1984·The New England Journal of Medicine·S P AndreoliD J Sherrard
Nov 1, 1982·The Journal of Urology·E B Ostroff, O W Chenault
Jun 1, 1994·Journal of Pharmacokinetics and Biopharmaceutics·J T DaltonJ L Au
Jan 1, 1993·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M Perazella, E Brown
Mar 1, 1993·The Journal of Urology·G F MurphyP J Henslee-Downey
Feb 1, 1990·Journal of Neuroendocrinology·G J Vries
Citations
Mar 17, 2006·The New England Journal of Medicine·Raymund L YongGayatri M Sreenivasan
Jun 6, 2006·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Marjorie S FriesenRobert D Gair
May 19, 2012·The Journal of Urology·Stephen J LukasewyczAseem R Shukla
Oct 20, 2009·Journal of Pediatric Urology·Sotirios BogrisImran Mushtaq
Mar 24, 2009·Journal of Pediatric Urology·Daniel B DeckerDuncan T Wilcox
Jul 29, 2008·Leukemia Research·Daniele FocosiMario Petrini
Jun 11, 2008·British Journal of Haematology·Christian HarkenseeClive Taylor
Apr 21, 2011·Pediatric Transplantation·Zuzana Hassan
Mar 10, 2000·Journal of Clinical Pharmacology·H NakamuraM D Reed
Feb 6, 2015·Korean journal of pediatrics·Seung Beom HanJin Han Kang
Feb 7, 2008·Nature Clinical Practice. Urology·Ardeshir R RastinehadLouis R Kavoussi
Jul 22, 2011·Journal of Toxicology·Jamal KamalovIrina Birman
Apr 29, 2016·Molecular and Clinical Oncology·Taito NakanoMikio Namiki
Apr 7, 2009·Journal of Pediatric Hematology/oncology·Sotirios L BogrisImran Mushtaq