Alveolar rhabdomyosarcoma of the uterine cervix

Gynecologic Oncology
J EmerichT Konefka

Abstract

Alveolar rhabdomyosarcoma is an uncommon tumor occurring mostly in extremities of children and adolescents. This type of tumor located in the uterine cervix has not been reported previously. A case of pure alveolar rhabdomyosarcoma arising from the uterine cervix in a 45-year-old patient and having a very aggressive clinical course is described. The patient presented with rapidly progressive cervical tumor, which was originally diagnosed as mesonephroid adenocarcinoma. She was treated with a radical two-stage surgical procedure and postoperative external beam and intracavitary irradiation. Despite treatment, she developed metastatic disease and died 3 months after the surgery. The aggressive course of the disease at this location was consistent with that of the majority of alveolar rhabdomyosarcoma cases of other sites reported in literature. No standard effective treatment is known for this tumor in adult patients.

Citations

May 28, 2011·Pathology International·Masaharu Fukunaga
Oct 23, 2016·Journal de gynécologie, obstétrique et biologie de la reproduction·J-B GuyN Magné
Feb 22, 2005·Gynecologic Oncology·Ashley S CaseWarner K Huh
Feb 28, 2002·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·W Glenn McCluggageH Lamki
Jun 27, 2008·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Francesco RivasiGiuseppe Masellis
Aug 26, 1998·The Journal of Obstetrics and Gynaecology Research·J X QiangT Tanaka

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