Always flush the sampling port before flushing the arterial cannula in pediatric patients

Acta Anaesthesiologica Scandinavica
M WeissO Baenziger


Blood sampling from arterial lines is a frequent event in anesthesia and critical care. To avoid clot formation, both the stopcock outlet and the cannula must be flushed after sampling. We investigated in a bench experiment whether fluid flow through the cannula is affected by the sequence of flushing procedures. Continuity of fluid delivery from a vascular cannula was gravimetrically determined using two different flushing techniques with either a syringe pump flush system or a bag flush system. The procedures comprised first flushing the stopcock towards the cannula and then towards the stopcock sampling outlet or the reverse order. Experiments were repeated in triplicate and two sets for each flushing system at hydrostatic pressures of 37 mm Hg and 74 mm Hg. The main finding of the study was that flushing the stopcock towards the outlet after flushing the cannula resulted in considerable retrograde aspiration volumes and zero flow times, in particular in combination with syringe pump flush systems. At a hydrostatic pressure of 74 mm Hg, the observed zero flow time at the cannula tip amounted to (mean+/-SD) 0.1+/-0.01 min with the bag flush system and 7.7+/-0.5 min with the syringe pump flush system. The related retrograde as...Continue Reading


Jun 1, 1977·The Annals of Thoracic Surgery·R M GardnerJ S Clark
Dec 1, 1987·Critical Care Medicine·H SelldénB Ekström-Jodal
Jan 1, 1985·Journal of Clinical Monitoring·K H Wesseling, N T Smith
Jul 12, 1969·Lancet·D GaanM P Mahoney
Dec 16, 1971·The New England Journal of Medicine·E LowensteinH H Lo
Dec 1, 1970·Journal of Applied Physiology·R M GardnerW D Gaisford
Oct 1, 1982·Anesthesia and Analgesia·K A Haselby, S F Dierdorf
Oct 1, 1980·Critical Care Medicine·J F EdmondsA W Conn


Dec 15, 2006·Annales Françaises D'anesthèsie Et De Rèanimation·M RiachyG Khayat
Sep 10, 2015·Biomedizinische Technik. Biomedical Engineering·Roland A SnijderAnnemoon D Timmerman

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