PMID: 20112213Jan 30, 2010Paper

Alzheimer's disease and hearing loss

Revista de neurologia
Carlos Gimeno-Vilar, Francisco J Cervera-Paz

Abstract

Despite the different epidemiological, neurophysiological and morphological studies published in the literature, it is still not known for sure whether there is a relation between Alzheimer's disease (AD) and peripheral hearing loss. In this work we conduct an auditory study in patients with AD and in volunteer controls in order to investigate this possible relationship. The sample studied consisted of 14 patients with a clinical diagnosis of probable AD (age: 79 Y 6 years) and 14 volunteers (age: 76 Y 5 years) who visited the Clinica Universidad de Navarra. After applying a set of thorough criteria to preclude any previous hearing problems, all the participants underwent a subjective hearing assessment by means of pure-tone threshold audiometry and vocal audiometry and an objective auditory assessment using a tympanometry study, stapedial reflex, otoacoustic emissions and brainstem auditory evoked potentials. For the analysis, patients with AD and controls were paired homogenously by sex and age. The main obstacle hindering the study was to recruit the participants, due to the fact that they did not see any direct benefit from the study and it demanded an excessive amount of their time. Pure-tone threshold audiometry showed th...Continue Reading

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