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Alzheimer's disease tau is a prominent pathology in LRRK2 Parkinson's disease

Acta Neuropathologica Communications

Nov 16, 2019

Michael X HendersonVirginia M Y- Lee

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Abstract

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson's disease (PD). While the clinical presentation of LRRK2 mutation carriers is similar to that of idiopathic PD (iPD) patients, the neuropathology of LRRK2 PD is less clearly defined. Lewy b...read more

Mentioned in this Paper

Alzheimer's Disease
Clinical Trials
Parkinson Disease
Pathology
Tau Proteins
Idiopathic Disease
Alpha-Synuclein
Pathogenesis
Neuropathology
Analysis
20
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Alzheimer's disease tau is a prominent pathology in LRRK2 Parkinson's disease

Acta Neuropathologica Communications

Nov 16, 2019

Michael X HendersonVirginia M Y- Lee

PMID: 31733655

DOI: 10.1186/s40478-019-0836-x

Abstract

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson's disease (PD). While the clinical presentation of LRRK2 mutation carriers is similar to that of idiopathic PD (iPD) patients, the neuropathology of LRRK2 PD is less clearly defined. Lewy b...read more

Mentioned in this Paper

Alzheimer's Disease
Clinical Trials
Parkinson Disease
Pathology
Tau Proteins
20
1

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