Ambient air pollution and the prevalence of rhinoconjunctivitis in adolescents: a worldwide ecological analysis

Air Quality, Atmosphere, & Health
Barbara K ButlandISAAC Phase Three Study Group

Abstract

Whether exposure to outdoor air pollution increases the prevalence of rhinoconjunctivitis in children is unclear. Using data from Phase Three of the International Study of Asthma and Allergies in childhood (ISAAC), we investigated associations of rhinoconjunctivitis prevalence in adolescents with model-based estimates of ozone, and satellite-based estimates of fine (diameter < 2.5 μm) particulate matter (PM2.5) and nitrogen dioxide (NO2). Information on rhinoconjunctivitis (defined as self-reported nose symptoms without a cold or flu accompanied by itchy watery eyes in the past 12 months) was available on 505,400 children aged 13-14 years, in 183 centres in 83 countries. Centre-level prevalence estimates were calculated and linked geographically with estimates of long-term average concentrations of NO2, ozone and PM2.5. Multi-level models were fitted adjusting for population density, climate, sex and gross national income. Information on parental smoking, truck traffic and cooking fuel was available for a restricted set of centres (77 in 36 countries). Between centres within countries, the estimated change in rhinoconjunctivitis prevalence per 100 children was 0.171 (95% confidence interval: - 0.013, 0.354) per 10% increase in ...Continue Reading

References

Jun 28, 2002·European Journal of Epidemiology·E A MitchellUNKNOWN ISAAC Phase One Study Group. International Study of Asthma and Allergy in Childhood
Feb 18, 2005·Nature Immunology·Andrew Saxon, David Diaz-Sanchez
Dec 8, 2009·American Journal of Respiratory and Critical Care Medicine·Ulrike GehringBert Brunekreef
Jan 6, 2010·Environmental Health Perspectives·Bert BrunekreefUNKNOWN ISAAC Phase 3 Study Group
Jan 16, 2010·The European Respiratory Journal·C Pénard-MorandI Annesi-Maesano
May 3, 2012·Environmental Health Perspectives·H Ross AndersonIsaac Phase One
Aug 14, 2012·Current Opinion in Allergy and Clinical Immunology·Chris Carlsten, Erik Melén
Jan 17, 2014·The Lancet. Respiratory Medicine·Gary W K WongUNKNOWN ISAAC Phase Three Study Group
Apr 2, 2018·Environment International·Emilie BurteBénédicte Jacquemin

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Citations

Jul 11, 2019·Clinics·Nelson A RosarioIgnacio Ansotegui

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