Ambient analysis of saturated hydrocarbons using discharge-induced oxidation in desorption electrospray ionization.

Journal of the American Society for Mass Spectrometry
Chunping WuR Graham Cooks

Abstract

Saturated nonfunctionalized hydrocarbons can be oxidized in situ by initiating an electrical discharge during desorption electrospray ionization (DESI) to generate the corresponding alcohols and ketones. This form of reactive DESI experiment can be utilized as an in situ derivatization method for rapid and direct analysis of alkanes at atmospheric pressure without sample preparation. Betaine aldehyde was incorporated into the DESI spray solution to improve the sensitivity of detecting the long-chain alcohol oxidation products. The limit of detection for alkanes (C(15)H(32) to C(30)H(62)) from pure samples is approximately 20 ng. Multiple oxidations and dehydrogenations occurred during the DESI discharge, but no hydrocarbon fragmentation was observed, even for highly branched squalane. Using exact mass measurements, the technique was successfully implemented for analysis of petroleum distillates containing saturated hydrocarbons.

References

Aug 1, 1993·Rapid Communications in Mass Spectrometry : RCM·K MorandM Mann
Jun 8, 2001·Journal of Mass Spectrometry : JMS·J H GrossA Dallos
Dec 31, 2002·Journal of the American Society for Mass Spectrometry·Juan ZhangRenato Zenobi
Jun 23, 2006·The Journal of Physical Chemistry. a·Daniela AscenziPaolo Tosi
Jan 26, 2007·Analytical Chemistry·Maolian Chen, Kelsey D Cook
Jul 13, 2007·Journal of the American Chemical Society·Penggao DuanHilkka I Kenttämaa
Oct 9, 2007·Analytical Chemistry·Guangming HuangZheng Ouyang
Jan 11, 2008·Analytical Chemistry·Sofie P PasilisGary J Van Berkel
Jan 12, 2008·Journal of the American Society for Mass Spectrometry·Marcela NefliuR Graham Cooks
Oct 7, 2008·Proceedings of the National Academy of Sciences of the United States of America·Alan G Marshall, Ryan P Rodgers
Mar 12, 2009·Analytical and Bioanalytical Chemistry·Leonard NyadongFacundo M Fernández

❮ Previous
Next ❯

Citations

Jun 4, 2010·Analytical and Bioanalytical Chemistry·Rosana M AlbericiMarcos N Eberlin
Nov 12, 2010·Analytical and Bioanalytical Chemistry·Ayanna U JacksonR Graham Cooks
Apr 6, 2011·Analytical and Bioanalytical Chemistry·Andrea PennaGiovanni Predieri
Apr 8, 2011·Journal of the American Society for Mass Spectrometry·Chang-Ching ChanAthula B Attygalle
Mar 15, 2012·Journal of the American Society for Mass Spectrometry·Jinshan GaoHilkka I Kenttämaa
Aug 22, 2012·Journal of the American Society for Mass Spectrometry·Kevin A DouglassAndre R Venter
Feb 12, 2013·Journal of the American Society for Mass Spectrometry·Robert B Cody, A John Dane
Jun 15, 2010·Journal of the American Society for Mass Spectrometry·Chang-Ching ChanAthula B Attygalle
May 24, 2013·Analytical Chemistry·Konstantin O ZhurovYury O Tsybin
Oct 4, 2015·Journal of the American Society for Mass Spectrometry·Wanderson RomãoBrice Bouyssiere
Sep 22, 2012·Mass Spectrometry Reviews·Chunping WuDemian R Ifa
Mar 16, 2013·Rapid Communications in Mass Spectrometry : RCM·Mario BenassiBernhard Spengler
Nov 17, 2010·Rapid Communications in Mass Spectrometry : RCM·J Larry Campbell
Jul 22, 2014·Journal of Mass Spectrometry : JMS·Petra HorkáJosef Cvačka
Apr 30, 2013·Progress in Lipid Research·Shane R EllisTodd W Mitchell
Feb 3, 2011·Chemical Communications : Chem Comm·Anyin LiR Graham Cooks
Dec 8, 2016·Journal of the American Society for Mass Spectrometry·Qiaoli LiangCarolyn J Cassady
Aug 1, 2018·Analytical Chemistry·Fred A M G van GeenenMichel W F Nielen
May 3, 2011·Analytical Chemistry·Ryan P Rodgers, Amy M McKenna
Apr 30, 2019·Analytical Chemistry·Dmytro S KulykAbraham K Badu-Tawiah

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.