Ambient fine particulate matter air pollution and the risk of hospitalization among COVID-19 positive individuals: Cohort study.

Environment International
Benjamin BoweZiyad Al-Aly

Abstract

Ecologic analyses suggest that living in areas with higher levels of ambient fine particulate matter air pollution (PM2.5) is associated with higher risk of adverse COVID-19 outcomes. Studies accounting for individual-level health characteristics are lacking. We leveraged the breadth and depth of the US Department of Veterans Affairs national healthcare databases and built a national cohort of 169,102 COVID-19 positive United States Veterans, enrolled between March 2, 2020 and January 31, 2021, and followed them through February 15, 2021. Annual average 2018 PM2.5 exposure, at an approximately 1 km2 resolution, was linked with residential street address at the year prior to COVID-19 positive test. COVID-19 hospitalization was defined as first hospital admission between 7 days prior to, and 15 days after, the first COVID-19 positive date. Adjusted Poisson regression assessed the association of PM2.5 with risk of hospitalization. There were 25,422 (15.0%) hospitalizations; 5,448 (11.9%), 5,056 (13.0%), 7,159 (16.1%), and 7,759 (19.4%) were in the lowest to highest PM2.5 quartile, respectively. In models adjusted for State, demographic and behavioral factors, contextual characteristics, and characteristics of the pandemic a one in...Continue Reading

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Citations

Sep 23, 2021·European Journal of Clinical Investigation·Agostino Di CiaulaPiero Portincasa
Sep 3, 2021·Journal of the American Society of Nephrology : JASN·Benjamin BoweZiyad Al-Aly
Nov 5, 2021·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jennifer Perret, Shyamali Dharmage
Nov 5, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Roberto BergamaschiUNKNOWN MuSC-19 study group
Nov 20, 2021·Environmental Health Perspectives·Anna L Hansell, Paul J Villeneuve

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