Ambulation and survival following surgery in elderly patients with metastatic epidural spinal cord compression

The Spine Journal : Official Journal of the North American Spine Society
Eyal ItshayekJosé E Cohen

Abstract

Metastatic epidural spinal cord compression (MESCC) is a disabling consequence of disease progression. Surgery can restore or preserve physical function, improving access to treatments that increase duration of survival; however, advanced patient age may deter oncologists and surgeons from considering surgical management. Evaluate the duration of ambulation and survival in elderly patients following surgical decompression of MESCC. Retrospective file review of a prospective database, under institutional review board (IRB) waiver of informed consent, of consecutive patients treated in an academic tertiary care medical center from August 2008 to March 2015. Patients ≥65 years presenting neurological and/or radiological signs of cord compression because of metastatic disease, who underwent surgical decompression. Duration of ambulation and survival. Patients underwent urgent multidisciplinary evaluation and surgery. Ambulation and survival were compared with age, pre-, and postoperative neurological (American Spinal Injury Association [ASIA] Impairment Scale [AIS]) and performance status (Karnofsky Performance Status [KPS]), and Tokuhashi Score using Kruskal-Wallis and Wilcoxon signed rank tests, Pearson correlation coefficient, C...Continue Reading

Citations

Aug 3, 2018·Skeletal Radiology·Antonio LeoneCesare Colosimo
Aug 10, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·C BouthorsUNKNOWN SOFCOT
May 17, 2021·The Spine Journal : Official Journal of the North American Spine Society·Lananh NguyenAndrew J Schoenfeld

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