Ambulatory arterial stiffness index: reproducibility of different definitions

American Journal of Hypertension
George S StergiouLeonidas G Roussias

Abstract

Ambulatory arterial stiffness index (AASI) has been proposed as a marker of arterial stiffness, which predicts cardiovascular mortality. This study compared the reproducibility of 24-h, daytime, night time, and symmetrical AASI. A total of 126 untreated hypertensives (mean age 48.2 +/- 10.7 (s.d.) years, 70 men) underwent 24-h ambulatory blood pressure (ABP) monitoring twice 2-4 weeks apart. The reproducibility of AASI was assessed using the following criteria: (i) repeatability coefficient (RC = 2 x s.d. of differences); (ii) RC expressed as a percentage of close to maximal variation (pMV = RC/(4 x s.d. of the mean of paired recordings)); (iii) coefficient of variation (CV); (iv) concordance correlation coefficient (CCC); (v) agreement (kappa) between the two AASI measurements to detect subjects at the top quartile of the respective AASI distributions. There was no difference in average AASI values between the two assessments. For 24-h, daytime, night time, and symmetrical AASI, respectively, (i) RC values were 0.24, 0.38, 0.42, and 0.30; (ii) pMV 49.6, 68.8, 73.9, and 56; (iii) CV 40.3, 39.3, 62.9, and 116.3; (iv) CCC 0.60, 0.35, 0.28, and 0.52; (v) agreement 82.5% (kappa 0.54), 72.2% (0.28), 73% (0.22), and 81.7% (0.50). Dif...Continue Reading

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Citations

Oct 1, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·George S StergiouLeonidas G Roussias
May 1, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·George S StergiouLeonidas G Roussias
Jul 6, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Gianfranco Parati, Miriam Revera
Jan 31, 2012·BMC Cardiovascular Disorders·Manuel Angel Gómez-MarcosUNKNOWN Vasorisk group
Jun 8, 2012·International Journal of Hypertension·Ronaldo Altenburg GismondiRachel Bregman
Mar 27, 2015·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Anastasios KolliasGeorge S Stergiou
May 9, 2012·Scandinavian Journal of Clinical and Laboratory Investigation·Lene BoesbyAnne-Lise Kamper
Sep 26, 2014·Renal Failure·Shu ZhangChang-Ying Xing
Jul 14, 2016·American Journal of Hypertension·Benjamin Gavish, Joseph L Izzo
Jan 21, 2010·American Journal of Hypertension·Yan LiJan A Staessen

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