Ambulatory blood pressure and heart rate in hypertensives with renal failure: comparison between diabetic nephropathy and non-diabetic glomerulopathy

Clinical and Experimental Hypertension : CHE
Kouichi TamuraSatoshi Umemura

Abstract

The purpose of this study was to examine a possible difference in the 24-h blood pressure (BP) profile between hypertensives with diabetic nephropathy (DN) and those with non-diabetic glomerulopathy (non-DN). We measured 24-h ambulatory BP in 34 type 2 DN and 34 non-DN patients who were hospitalized for the educational program in our hospital. There were no significant differences in 24-h and daytime systolic BP between DN (143 vs. 136 mmHg, NS for 24-h systolic BP) and non-DN (143 vs. 138 mmHg, NS for daytime systolic BP). Although both groups disclosed blunted nocturnal decrease in BP and were classified as "non-dipper" type, DN patients had a significantly higher nighttime systolic BP than patients with non-DN (142 vs. 132 mmHg, p = 0.0217). BP and heart rate (HR) variabilities were also estimated, and patients with DN showed a reduced nighttime HR variability than those with non-DN (4.8 vs. 6.6 beats/min, p = 0.0115). DN patients had an increase in urinary protein excretion (3.0 vs. 1.4 g/day, p = 0.0095) and a decrease in serum albumin concentration (3.1 vs. 3.7 mg/dl, p < 0.0001). Furthermore, urinary protein excretion was significantly correlated with nighttime systolic BP (r = 0.480, p = 0.0031) but not with nighttime H...Continue Reading

References

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Dec 28, 2006·Clinical and Experimental Hypertension : CHE·Kouichi TamuraSatoshi Umemura

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Citations

Aug 29, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Shin-ichiro MasudaSatoshi Umemura
Nov 17, 2012·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Mai YanagiSatoshi Umemura
Apr 22, 2008·Clinical and Experimental Hypertension : CHE·Motoko OzawaSatoshi Umemura
Jan 29, 2016·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kouichi TamuraSatoshi Umemura
Oct 16, 2012·Clinical Transplantation·Kevin C Wen, Sita Gourishankar
Nov 13, 2009·Diabetes Care·Gianfranco Parati, Grzegorz Bilo
Jun 10, 2009·Expert Review of Cardiovascular Therapy·Rajiv Vij, Aldo J Peixoto
Aug 4, 2019·The Journal of Clinical Hypertension·Kouichi TamuraHiromichi Wakui
Dec 14, 2018·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hiroshi KadoKeiichi Tamagaki

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