Ambulatory esophageal manometry/pH-metry discriminates between patients with different esophageal symptoms

Digestive Diseases and Sciences
W G PatersonH Wang

Abstract

Ambulatory esophageal manometry/pH-metry has been used primarily in patients with chest pain of presumed esophageal origin, and it is unclear whether the discriminating power of this test applies to other esophageal symptoms. In the present study, prolonged ambulatory manometry/pH recordings were compared in 17 healthy controls, 12 patients with atypical chest pain, and 11 patients with chest pain and nonstructural dysphagia using the Synectics microdigitrapper system. Chest pain patients tended to have higher values for all the pH variables, but their esophageal motility parameters were no different than controls. On the other hand, the chest pain plus dysphagia group was characterized by a significantly lower proportion of propagated contractions between 10 and 5 cm above the lower esophageal sphincter. This group also tended to have a higher frequency of high-amplitude or prolonged-duration contractions. In comparison to the results of standard stationary esophageal manometry, the prolonged ambulatory recordings were more sensitive in detecting esophageal motor dysfunction in the two patient groups. This study suggests that quantitative analysis of ambulatory pH/motility recordings is a sensitive method of evaluating patient...Continue Reading

References

Nov 1, 1989·Digestive Diseases and Sciences·E E SofferD L Wingate
May 1, 1993·Digestive Diseases and Sciences·W G PatersonL R Da Costa
Jan 1, 1965·Archives of Oral Biology·C S LEARC F MOORREES

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Citations

Mar 6, 2002·Alimentary Pharmacology & Therapeutics·W-M WongS K Lam
Jan 22, 2004·Journal of Pediatric Gastroenterology and Nutrition·Denesh K ChitkaraSamuel Nurko

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