PMID: 20127046Feb 4, 2010Paper

Amelioration of asthmatic inflammation by an aqueous extract of Spinacia oleracea Linn

International Journal of Molecular Medicine
Jin-Chul HeoSang-Han Lee

Abstract

Inflammation of the respiratory tract is a crucial process in immune diseases, including asthma, and atopic rhinitis. To establish whether an aqueous extract of Spinacia oleracea Linn (SoL) has a beneficial influence in terms of anti-asthmatic activity, we examined its effects on an ovalbumin-induced asthmatic model. Mice sensitized to ovalbumin were orally administered the SoL extract, and their lungs examined by hematoxylin and eosin staining to determine IL-4/13 cytokine expression. The SoL extract exerted strong anti-asthmatic effects by inducing a decrease in the CD4+ cell number, IL-4/13, and other molecular markers in the lung. Our results collectively indicate that the aqueous SoL extract ameliorates asthmatic symptoms effectively in a mouse ovalbumin-challenge model.

Citations

Jan 12, 2012·Inflammopharmacology·Kishor Vasant OtariChandrashekhar Devidas Upasani
Nov 6, 2012·Food Chemistry·Momoko IshidaTakuya Sugahara
Feb 11, 2012·Korean journal of pediatrics·Do Kyun Kim

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