Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells

Neuroreport
S ChanvitayapongsA Y Sun

Abstract

The goal of this study was to investigate the effect of resveratrol, an active ingredient found in grapes and other plant products, in ameliorating oxidative stress. Oxidative stress was induced by addition of Fe2+ and t-butyl hydroperoxide to the cultured PC12 cell medium. Resveratrol, vitamins C and/or E, were added to the cell culture medium during oxidative stress. The combination of resveratrol and vitamins C and/or E was more effective in protecting the cell than was any of these three antioxidants alone.

References

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Mar 1, 1985·Alcoholism, Clinical and Experimental Research·G Y Sun, A Y Sun
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Citations

May 5, 1998·Molecular and Chemical Neuropathology·B Draczynska-LusiakA Y Sun
Jan 13, 2004·Neurotoxicity Research·A Y SunG Y Sun
Feb 2, 2013·Journal of Neural Transmission·Prabhakar OrsuAnnapurna Akula
Feb 5, 2009·Neuromolecular Medicine·Albert Y SunGrace Y Sun
Mar 23, 2010·Molecular Neurobiology·Albert Y SunGrace Y Sun
Nov 5, 2003·Brain Research Bulletin·Angela ConteDavide Tagliazucchi
May 10, 2003·Life Sciences·Si Eun LeeJeong Hee Kim
Feb 19, 2000·Life Sciences·L Frémont
Jan 29, 2002·Pharmacology, Biochemistry, and Behavior·Y K GuptaGeeta Chaudhary
Nov 5, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael SeidmanWayne S Quirk
Feb 5, 2003·Cancer Letters·Richard M NilesGary G Meadows
Mar 14, 2000·Toxicology Letters·H BabichH L Zuckerbraun
Jul 8, 2000·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M RenisA Russo
Feb 14, 2002·Free Radical Biology & Medicine·Albert Y SunGrace Y Sun
Sep 19, 1998·Free Radical Biology & Medicine·J S Kim-Han, A Y Sun
Aug 8, 2002·The Journal of Nutritional Biochemistry·D ButterfieldVittorio Calabrese
Jun 10, 2008·Expert Reviews in Molecular Medicine·Imran AhmadHing Y Leung
Jan 12, 2001·Clinical and Experimental Pharmacology & Physiology·K MizutaniY Yamori
Sep 27, 2003·Epilepsia·Antonino Pavone, Venera Cardile
Jul 8, 2011·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Monica Rosa LoizzoFrancesco Menichini
Sep 8, 2010·Rejuvenation Research·Mark E ObrenovichV Prakash Reddy
Mar 13, 2001·Journal of Cardiovascular Pharmacology·L GiovanniniA Bertelli
Nov 1, 2002·Journal of Cardiovascular Pharmacology·Jianhua CuiDipak K Das
Oct 1, 2008·Journal of Gastroenterology and Hepatology·Paola VitaglioneVincenzo Fogliano
Jun 8, 2001·Alcoholism, Clinical and Experimental Research·A Y SunG Y Sun

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