Ameloblastic fibrosarcoma of the mandible: report of two cases and review of the literature

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
R C BregniA M García

Abstract

Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic tumour. To date, 60 well-documented cases have been published in the English-language literature. Two additional cases located in the posterior region of the mandible are reported. The relevant clinicopathological features of these cases, as well as those previously reported are discussed. Approximately two-thirds of AFS are malignant tumors de novo, with an average age of the affected patients being 22.9 years. This age is lower than the one observed in AFS developing from a pre-existent benign lesion (mean 33 years). Although regional and distant metastases are very infrequent, AFS is a locally aggressive lesion, with 23 (37%) of the reported cases having at least one recurrence; 12 patients (19.3%) died of the disease. Wide surgical excision with long-term follow-up remains the treatment of choice for this neoplasm.

Citations

Jul 8, 2011·Medical Oncology·Bulent CetinMustafa Benekli
Feb 19, 2004·Oral Oncology·Martin KunkelWilfried Wagner
Oct 20, 2011·Journal of Pediatric Hematology/oncology·Charlotte Demoor-GoldschmidtNadege Corradini
Feb 28, 2014·Journal of Oral and Maxillofacial Pathology : JOMFP·Akindayo O AkinyamojuB Kolude
Jun 24, 2011·Dento Maxillo Facial Radiology·S WangQ Yu
Aug 14, 2008·Expert Review of Anticancer Therapy·Alexander D Rapidis
May 1, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Roseanna NoordhoekDaniel M Laskin
Dec 20, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Jonathan LaiHagen Klieb
Feb 27, 2010·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Giacomo De RiuAntonio Tullio
Jan 20, 2009·International Journal of Oral and Maxillofacial Surgery·P MainentiL E B Rosa
Feb 19, 2008·Journal of Pediatric Surgery·Nona ZabolinejadAlale Shojae Razavi
Jun 20, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Michelle D WilliamsAdel K El-Naggar
Apr 9, 2005·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Ok-Jun LeeKyung-Ja Cho
Jul 16, 2011·Diagnostic Cytopathology·Nalini GuptaKim Vaiphei
Jun 5, 2013·Oral Diseases·M Martínez MartínezO P de Almeida
Sep 1, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Aisha KousarKhurram Minhas
Nov 29, 2015·Oral and Maxillofacial Surgery Clinics of North America·Joshua M Abrahams, Shawn A McClure
Sep 1, 2005·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Kazuo KobayashiAkiyoshi Hirano
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Lee J Slater
Sep 24, 2015·Brazilian Journal of Otorhinolaryngology·Leorik Pereira da SilvaAna Paula Veras Sobral
Jul 13, 2013·European Annals of Otorhinolaryngology, Head and Neck Diseases·S M GilaniB M Al-Khafaji
Jul 26, 2014·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Douglas Magno GuimarãesFabio Daumas Nunes
Aug 21, 2015·The American Journal of Case Reports·Zhaleh MohsenifarFatemeh Mashhadi Abbas
Apr 30, 2015·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Al Haitham Al ShetawiMark L Urken
Apr 11, 2015·Case Reports in Pathology·Abelardo Loya-SolisOralia Barboza-Quintana
May 1, 2016·European Annals of Otorhinolaryngology, Head and Neck Diseases·S-J ChenH Liu
Aug 27, 2016·Annals of Maxillofacial Surgery·Antti KirjavainenGeorge K Sándor
May 12, 2017·Brazilian Dental Journal·João Paulo Silva ServatoAdriano Mota Loyola
Nov 4, 2009·The Journal of Craniofacial Surgery·Bharat GuthikondaSujit S Prabhu
Aug 3, 2017·BMJ Case Reports·Nkhensani Yvonne ChaukeElias Ndobe
Oct 8, 2014·Experimental and Therapeutic Medicine·Yuan-Yuan HuYu-Ming Niu
Mar 12, 2019·Annals of Plastic Surgery·Dana Rioux-ForkerArshad R Muzaffar
Mar 31, 2016·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Sunil AgarwalYash Patil
Dec 4, 2019·Frontiers in Veterinary Science·Emma BelleiMargherita Gracis
Apr 27, 2017·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Michael OertelHans Theodor Eich

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
P DalleraA Campobassi
Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
Kazuo KobayashiAkiyoshi Hirano
© 2021 Meta ULC. All rights reserved