PMID: 19871660Jul 31, 1947

AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B

The Journal of Experimental Medicine
C A KNIGHT

Abstract

Microbiological assays for amino acids were made on hydrolysates of four to five highly purified preparations each of influenza A virus (PR8 strain) and influenza B virus (Lee strain). The results of the assays indicated that these strains of influenza virus contain approximately the same amounts of alanine, aspartic acid, glycine, histidine, isoleucine, leucine, methionine, phenylalanine, proline, serine, threonine, and valine. However, significant differences were found in the values for arginine, glutamic acid, lysine, tryptophane, and tyrosine. It is believed that these differences may provide, at least in part, a chemical explanation for some of the differing properties of the PR8 and Lee strains of influenza viruses.

References

Nov 1, 1940·Science·T Francis
Mar 1, 1944·The Journal of Experimental Medicine·W M Stanley
Apr 1, 1946·The Journal of Experimental Medicine·C A KNIGHT

Citations

Jan 1, 1959·Archiv für Mikrobiologie·M K TOLBA, J K ESKAROUS
Jan 1, 1952·Archiv für die gesamte Virusforschung·C A KNIGHT
Jan 1, 1955·Archiv für die gesamte Virusforschung·J HIRTZ
Jan 1, 1962·Archiv für die gesamte Virusforschung·A KOCH
Jan 15, 1980·Virology·A H Erickson, E D Kilbourne
Dec 17, 1949·Nature·R MARKHAM, J D SMITH
Jan 1, 1963·Acta Pathologica Et Microbiologica Scandinavica·A HARBOE

Related Concepts

Myxoviruses
Alanine
Arginine
Aspartic Acid
Glycine
Histidine
Isoleucine
Leucine
Lysine
Methionine

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