Amino acids that centrally influence blood pressure and regional blood flow in conscious rats.

Journal of Amino Acids
Yumi Takemoto


Functional roles of amino acids have increasingly become the focus of research. This paper summarizes amino acids that influence cardiovascular system via the brain of conscious rats. This paper firstly describes why amino acids are selected and outlines how the brain regulates blood pressure and regional blood flow. This section includes a concise history of amino acid neurotransmitters in cardiovascular research and summarizes brain areas where chemical stimulations produce blood pressure changes mainly in anesthetized animals. This is followed by comments about findings regarding several newly examined amino acids with intracisternal stimulation in conscious rats that produce changes in blood pressure. The same pressor or depressor response to central amino acid stimulations can be produced by distinct mechanisms at central and peripheral levels, which will be briefly explained. Thereafter, cardiovascular actions of some of amino acids at the mechanism level will be discussed based upon findings of pharmacological and regional blood flow measurements. Several examined amino acids in addition to the established neurotransmitter amino acids appear to differentially activate brain structures to produce changes in blood pressure...Continue Reading


Nov 23, 1979·European Journal of Pharmacology·J ChellyH Schmitt
Jan 1, 1977·Neuroscience·K J DormerH L Stone
Jun 1, 1976·The Journal of Physiology·W Feldberg, P G Guertzenstein
Oct 1, 1991·Neuroscience Research·D J BradleyK M Spyer
May 31, 1991·Brain Research·A J Verberne, H A Struyker Boudier
Feb 1, 1991·Journal of the Autonomic Nervous System·M Miura, K Takayama
May 1, 1991·Drugs·M D Wheeler, D M Styne
Jan 1, 1990·Brain Research Bulletin·R G DryeM L Woodruff
Jan 15, 1991·The Journal of Comparative Neurology·Y YasuiD F Cechetto
Jan 1, 1990·The Japanese Journal of Physiology·Y Takemoto
Nov 15, 1988·Brain Research·M Miura, K Takayama
Nov 30, 1989·Biochemical and Biophysical Research Communications·H H SchmidtE Böhme
Jan 1, 1989·The Japanese Journal of Physiology·Y Takemoto, J Iriuchijima
Mar 1, 1985·Stroke; a Journal of Cerebral Circulation·R D Piper, P J Goadsby
Jun 23, 1987·Brain Research·A F Sved, G Felsten
Mar 1, 1989·The American Journal of Physiology·J M CheekE D Crandall

❮ Previous
Next ❯


Mar 3, 2015·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Juan Antonio Pineda-JuárezAlberto Ronquillo-Martínez
Nov 20, 2012·Angewandte Chemie·Jayanta ChatterjeeHorst Kessler
Jun 18, 2020·Nutrients·Chien-Ning Hsu, You-Lin Tain
May 15, 2021·Journal of Nutrition and Metabolism·Demetra J Mills
Aug 19, 2021·Nature Communications·Taiyun KimJean Yee Hwa Yang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Brain Barrier Regulation in Health & Disease

The blood brain barrier is essential in regulating the movement of molecules and substances in and out of the brain. Disruption to the blood brain barrier and changes in permeability allow pathogens and inflammatory molecules to cross the barrier and may play a part in the pathogenesis of neurodegenerative disorders. Here is the latest research in this field.

Blood Brain Barrier Chips

The blood brain barrier (BBB) is comprised of endothelial cells that regulate the influx and outflux of plasma concentrations. Lab-on-a-chip devices allow scientists to model diseases and mechanisms such as the passage of therapeutic antibodies across the BBB. Discover the latest research on BBB chips here.

Blood Brain Barrier

The blood brain barrier is a border that separates blood from cerebrospinal fluid. Discover the latest search on this highly selective semipermeable membrane here.