Amino-Functionalized Ceramic Capillary Membranes for Controlled Virus Retention

Environmental Science & Technology
Julia BartelsKurosch Rezwan

Abstract

A straightforward chemical functionalization strategy using aminosilanes for high-flux yttria-stabilized zirconia capillary membranes is presented (macroporous, d50 = 144 nm, open porosity =49%, membrane flux ∼150 L/(m(2)hbar)). Three different aminosilanes with one, two or three amino groups per silane molecule, namely 3-aminopropyltriethoxysilane (APTES), N-(2-aminoethyl)-3-aminopropyltriethoxysilane (AE-APTES) and N-(3-trimethoxysilylpropyl)diethylenetriamine (TPDA), are used to generate the amino-functionalized membranes. With a higher number of amino groups per silane molecule increased loading capacities between 0.44 and 1.01 accessible amino groups/nm(2) membrane are achieved. Streaming potential measurements confirm that the zeta-potential of the membrane surface is converted from negative (non-functionalized) to positive (amino-functionalized). By operation in dead-end filtration mode using the model virus MS2 (diameter = 25 nm, IEP = 3.9) the virus retention capacity of the amino-functionalized membranes is significantly increased and log reduction values (LRVs) of up to 9.6 ± 0.3 (TPDA) are obtained whereas a LRV < 0.3 is provided by the non-functionalized membranes. Long-term dead-end filtration experiments for 1 we...Continue Reading

References

Mar 1, 1979·Applied and Environmental Microbiology·M D Sobsey, B L Jones
Jan 1, 1985·Applied and Environmental Microbiology·K S ZerdaS M Goyal
Apr 1, 1993·Applied Biochemistry and Biotechnology·K Yokoyama
Dec 16, 2003·International Journal of Food Microbiology·Marion Koopmans, Erwin Duizer
Dec 31, 2005·Environmental Science & Technology·Youwen YouYan Jin
Feb 9, 2008·Journal of Colloid and Interface Science·S FiorilliE Garrone
Dec 1, 2009·Biomaterials·Rebecca CademartiriMichael A Brook
Jan 15, 2010·Biotechnology and Bioengineering·George MiesegaesKurt Brorson
Jan 28, 2010·Journal of Applied Microbiology·B Michen, T Graule
Dec 9, 2010·International Journal of Environmental Research and Public Health·João P S Cabral
Jun 29, 2011·Water Research·Ian BradleyThanh H Nguyen
Jul 26, 2012·Environmental Science & Technology·Stephen KrollKurosch Rezwan
Jan 5, 2013·Environmental Science & Technology·Benjamin MichenThomas Graule
Apr 10, 2013·Acta Biomaterialia·Laura TreccaniKurosch Rezwan

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Citations

Aug 16, 2016·ACS Applied Materials & Interfaces·MingDong WangJiaJun Fu
Apr 19, 2018·Applied Spectroscopy·Johannes KieferKurosch Rezwan
Apr 6, 2021·ACS Applied Nano Materials·Henry A BlandOliver A Williams
Jul 20, 2018·ACS Omega·Gergő P SzekeresThomas Graule
Aug 19, 2020·ACS Applied Materials & Interfaces·Benjamin BesserJorg Thöming

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