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Aminoacyl-nucleotide reactions: studies related to the origin of the genetic code and protein synthesis

Origins of Life

Jan 1, 1984

David R MullinsJeffrey C Lacey

PMID: 6462695

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Abstract

In the present paper, we report on the effect of pH and carbonate on the hydrolysis rate constants of N-blocked and free aminoacyl adenylate anhydrides. Whereas the hydrolysis of free aminoacyl adenylates seems principally catalyzed by OH-, the hydrolysis of the N-blocked species is als...read more

Mentioned in this Paper

Protein Biosynthesis
Fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
Origin of Life
phenylalanyl-AMP anhydride
Peptide Biosynthesis
Hydrogen-Ion Concentration
Genetic Code
Anhydrides
Glycine
Adenylate
Paper Details
References
  • References10
  • Citations2
1

Aminoacyl-nucleotide reactions: studies related to the origin of the genetic code and protein synthesis

Origins of Life

Jan 1, 1984

David R MullinsJeffrey C Lacey

PMID: 6462695

DOI:

Abstract

In the present paper, we report on the effect of pH and carbonate on the hydrolysis rate constants of N-blocked and free aminoacyl adenylate anhydrides. Whereas the hydrolysis of free aminoacyl adenylates seems principally catalyzed by OH-, the hydrolysis of the N-blocked species is als...read more

Mentioned in this Paper

Protein Biosynthesis
Fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
Origin of Life
phenylalanyl-AMP anhydride
Peptide Biosynthesis

Related Papers

Paper Details
References
  • References10
  • Citations2
1

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