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Aminoacyl-nucleotide reactions: studies related to the origin of the genetic code and protein synthesis

Origins of Life

Jan 1, 1984

D W MullinsJ C Lacey

PMID: 6462695

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Abstract

In the present paper, we report on the effect of pH and carbonate on the hydrolysis rate constants of N-blocked and free aminoacyl adenylate anhydrides. Whereas the hydrolysis of free aminoacyl adenylates seems principally catalyzed by OH-, the hydrolysis of the N-blocked species is als...read more

Mentioned in this Paper

phenylalanyl-AMP anhydride
Anhydrides
Peptide Biosynthesis
Protein Biosynthesis
Glycine
Glycine (Plant)
Adenylate
11-dehydrocorticosterone
Nucleotides
Phosphaden
Paper Details
References
  • References10
  • Citations2
1

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Origins of life: conformational energy calculations on primitive tRNA nestling an amino acid

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Aminoacyl-nucleotide reactions: studies related to the origin of the genetic code and protein synthesis

Origins of Life

Jan 1, 1984

D W MullinsJ C Lacey

PMID: 6462695

DOI:

Abstract

In the present paper, we report on the effect of pH and carbonate on the hydrolysis rate constants of N-blocked and free aminoacyl adenylate anhydrides. Whereas the hydrolysis of free aminoacyl adenylates seems principally catalyzed by OH-, the hydrolysis of the N-blocked species is als...read more

Mentioned in this Paper

phenylalanyl-AMP anhydride
Anhydrides
Peptide Biosynthesis
Protein Biosynthesis
Glycine
Glycine (Plant)
Adenylate
11-dehydrocorticosterone
Nucleotides
Phosphaden

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Related Papers

Journal of Theoretical Biology

Origins of life: conformational energy calculations on primitive tRNA nestling an amino acid

Journal of Theoretical BiologyMarch 7, 1985
R Balasubramanian, P Seetharamulu
Paper Details
References
  • References10
  • Citations2
1

Download from

PubMed
/papers/aminoacyl-nucleotide-reactions-studies-related-to/6462695