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Aminoacylation of coenzyme A and pantetheine by aminoacyl-tRNA synthetases: possible link between noncoded and coded peptide synthesis

Biochemistry

May 16, 1998

Hieronim Jakubowski

Abstract

Isoleucyl-tRNA synthetase (IleRS) catalyzes transfer of isoleucine from the enzyme-bound Ile-AMP and Ile-tRNA to the thiol group of coenzyme A, forming a thioester, Ile-S-CoA. Identity of Ile-S-CoA has been confirmed by several enzymatic and chemical tests. The synthesis of Ile-S-CoA, l...read more

Mentioned in this Paper

IARS gene
MARS gene
Chemical Procedure
Aminoacylation
Amino Acyl-tRNA Synthetases
MT-TA gene
Isoleucine
Isoleucine-tRNA Ligase
Ligase
Pantetheine
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Aminoacylation of coenzyme A and pantetheine by aminoacyl-tRNA synthetases: possible link between noncoded and coded peptide synthesis

Biochemistry

May 16, 1998

Hieronim Jakubowski

PMID: 9548745

DOI: 10.1021/bi972528v

Abstract

Isoleucyl-tRNA synthetase (IleRS) catalyzes transfer of isoleucine from the enzyme-bound Ile-AMP and Ile-tRNA to the thiol group of coenzyme A, forming a thioester, Ile-S-CoA. Identity of Ile-S-CoA has been confirmed by several enzymatic and chemical tests. The synthesis of Ile-S-CoA, l...read more

Mentioned in this Paper

IARS gene
MARS gene
Chemical Procedure
Aminoacylation
Amino Acyl-tRNA Synthetases
MT-TA gene
Isoleucine
Isoleucine-tRNA Ligase
Ligase
Pantetheine

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123
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