PMID: 11931673Apr 5, 2002Paper

Aminoadipate reductase gene: a new fungal-specific gene for comparative evolutionary analyses

BMC Evolutionary Biology
Kwang-Deuk AnAkira Yokota

Abstract

In fungi, aminoadipate reductase converts 2-aminoadipate to 2-aminoadipate 6-semialdehyde. However, other organisms have no homologue to the aminoadipate reductase gene and this pathway appears to be restricted to fungi. In this study, we designed degenerate primers for polymerase chain reaction (PCR) amplification of a large fragment of the aminoadipate reductase gene for divergent fungi. Using these primers, we amplified DNA fragments from the archiascomycetous yeast Saitoella complicata and the black-koji mold Aspergillus awamori. Based on an alignment of the deduced amino acid sequences, we constructed phylogenetic trees. These trees are consistent with current ascomycete systematics and demonstrate the potential utility of the aminoadipete reductase gene for phylogenetic analyses of fungi. We believe that the comparison of aminoadipate reductase among species will be useful for molecular ecological and evolutionary studies of fungi, because this enzyme-encoding gene is a fungal-specific gene and generally appears to be single copy.

References

Dec 22, 1989·European Journal of Biochemistry·S SchäferG Fuchs

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Citations

Nov 9, 2006·Bioscience, Biotechnology, and Biochemistry·Hiromi Nishida
Apr 12, 2011·The Journal of General and Applied Microbiology·Hiromi NishidaJunta Sugiyama
May 27, 2008·Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan·Maiko WatanabeAkira Yokota
Aug 3, 2014·Applied and Environmental Microbiology·Daniel KalbDirk Hoffmeister
Jul 5, 2011·Journal of the Science of Food and Agriculture·Maiko WatanabeYukiko Hara-Kudo
Feb 28, 2006·Chembiochem : a European Journal of Chemical Biology·Torsten SchweckeHans von Döhren

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