Amiodarone-induced hepatitis: biological, histological diagnosis, development and role of associated factors. Review of the literature. Report of 2 cases

La Revue de médecine interne
J P RocheG Gay

Abstract

Two cases of pseudo-alcoholic amiodarone-induced hepatitis are reported. The authors mention the different clinical forms of the disease and describe its clinical, biochemical and histological features. They stress the unpredictable and discordant character of its course and the influence of associated pathological factors. The role played by Ito's cells in the genesis of the liver fibrosis observed in amiodarone toxicity is discussed.

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