Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor

Bioorganic & Medicinal Chemistry Letters
Shi XuMing Xian

Abstract

Ammonium tetrathiomolybdate (TTM) was found to be a slow hydrogen sulfide (H2S) releasing agent. Its H2S generation capability in aqueous solutions was confirmed by UV-vis and fluorescence assays. TTM also showed H2S-like cytoprotective effects in hydrogen peroxide (H2O2)-induced oxidative damage in HaCaT cells.

References

Apr 11, 2002·Chemical Reviews·Peng George WangAdam J Janczuk
Apr 11, 2002·Chemical Reviews·Anthony R Butler, Ian L Megson
Sep 22, 2007·Trends in Pharmacological Sciences·John L Wallace
Sep 8, 2010·The Journal of Organic Chemistry·Thanikachalam Gunasundari, Srinivasan Chandrasekaran
Jan 8, 2011·Annual Review of Pharmacology and Toxicology·Ling LiPhilip K Moore
Feb 9, 2012·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·M Scott Vandiver, Solomon H Snyder
Apr 16, 2013·Antioxidants & Redox Signaling·Khosrow Kashfi
Jul 16, 2013·Nitric Oxide : Biology and Chemistry·Gopi K KolluruChristopher G Kevil
Aug 7, 2013·Molecular BioSystems·Chung-Min ParkMing Xian
Jul 16, 2014·Chemical Communications : Chem Comm·Yu ZhaoMing Xian
Nov 27, 2014·Journal of Anaesthesiology, Clinical Pharmacology·Daniel G HottingerKumar G Belani
Apr 8, 2015·Nature Reviews. Drug Discovery·John L Wallace, Rui Wang
Sep 1, 2015·Journal of Medicinal Chemistry·Yu ZhaoMing Xian

❮ Previous
Next ❯

Citations

Feb 28, 2017·Medicinal Research Reviews·Yueqin ZhengBinghe Wang
Jun 10, 2017·Expert Reviews in Molecular Medicine·Francisco J Gil-BeaAinara Vallejo-Illarramendi
Mar 3, 2018·Cell Death & Disease·Sahar SheykhansariAjay Vikram Singh
Mar 30, 2019·British Journal of Pharmacology·Tom DurhamAlex Dyson
Apr 11, 2020·Intensive Care Medicine Experimental·Bruna Pescador MendonçaAlex Dyson
Dec 19, 2020·Intensive Care Medicine Experimental·Tamara MerzOscar McCook
Apr 4, 2021·Antioxidants·Angela CorvinoBeatrice Severino
Jun 3, 2021·Biomolecules·Saadullah KhattakDong-Dong Wu
Aug 7, 2021·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Wanjun GongQianjun He
Jan 26, 2018·ACS Applied Materials & Interfaces·Lucas-Alexandre SternXile Hu
Nov 8, 2017·Chemical Reviews·Milos R FilipovicRuma Banerjee
Oct 13, 2020·Inorganic Chemistry·Tobias J SherbowMichael D Pluth
Oct 6, 2021·Accounts of Chemical Research·Xiang NiMing Xian

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Ya-guang DingJun-bao Du
© 2022 Meta ULC. All rights reserved