PMID: 11927426Apr 3, 2002Paper

Amniotic membrane grafts for nontraumatic corneal perforations, descemetoceles, and deep ulcers

Ophthalmology
A SolomonScheffer C G Tseng

Abstract

To describe the clinical outcome of amniotic membrane transplantation (AMT) for nontraumatic corneal perforations, descemetoceles, and deep ulcers. Retrospective, noncomparative, interventional case series. Thirty-four eyes of 33 consecutive patients operated on for nontraumatic corneal perforations or descemetoceles at four academic departments of ophthalmology. Associated autoimmune disorders included rheumatoid arthritis (n = 6), Stevens-Johnson syndrome (n = 3), ocular cicatricial pemphigoid (n = 2), systemic lupus erythematosus (n = 1), and one eye with Mooren's ulcer, as well as neurotrophic, or exposure keratopathy (n = 10), postinfectious nonhealing ulcers (n = 6), and postsurgery (n = 5). Three or four layers of amniotic membrane (AM) were applied over the ulcer bed and anchored with 10-0 nylon interrupted or running sutures. A large AM piece was used as a patch to cover the entire corneal surface. Formation of anterior chamber depth, epithelialization of the AM grafts, and stability of the corneal stromal thickness. The mean follow-up period was 8.1 +/- 5.7 (ranging from 2-23) months. A successful result was observed in 28 of 34 eyes (82.3%). Of the successful cases, 23 eyes needed one AMT procedure, whereas 5 eyes ne...Continue Reading

References

Jul 1, 1990·Archives of Ophthalmology·J R NobeR E Smith
Jul 1, 1989·Survey of Ophthalmology·S L PortnoyH E Kaufman
Jan 1, 1984·International Ophthalmology Clinics·K R Kenyon, C W Roberts
May 1, 1983·Australian Journal of Ophthalmology·L W HirstE De Juan
Jun 1, 1983·Ophthalmology·J L WeissD J Doughman
Sep 1, 1981·American Journal of Ophthalmology·C S Foster, J Duncan
Mar 1, 1997·American Journal of Ophthalmology·S H Lee, S C Tseng
Dec 24, 1997·American Journal of Ophthalmology·S C TsengS H Lee
Apr 29, 1998·The New England Journal of Medicine·A LambiaseL Aloe
Oct 26, 1999·Archives of Ophthalmology·R T PiresD T Tan
May 16, 2000·Ophthalmology·D MellerS C Tseng
Jul 25, 2000·The British Journal of Ophthalmology·H J ChenS C Tseng
Feb 28, 2001·Journal of Cataract and Refractive Surgery·M X WangS C Tseng
Mar 10, 2001·American Journal of Ophthalmology·K HanadaK Tsubota

❮ Previous
Next ❯

Citations

Jul 19, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A A BialasiewiczA Thakral
Jan 16, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Thomas FuchslugerDaniel Meller
Sep 18, 2009·Veterinary Research Communications·Marissak KalpravidhSudson Sirivaidyapong
Jan 15, 2010·Journal of Ocular Biology, Diseases, and Informatics·Firoozeh RahimiReza Soltani Mogaddam
Nov 18, 2011·Journal of Ophthalmic Inflammation and Infection·Konstantinos T TsaousisIoannis T Tsinopoulos
Jun 28, 2011·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Miklós D ReschErzsébet Csányi
Jul 17, 2004·Cornea·M Teresa Rodríguez-AresFrancisco Gude
Sep 15, 2005·Cornea·Ganesha R Kandavel, Roy S Chuck
Nov 30, 2006·Cornea·Shigeyuki IjiriScheffer C G Tseng
Jan 2, 2007·Cornea·Jean-Jacques GicquelPaul Dighiero
Mar 1, 1990·Equine Veterinary Journal·D V HackerH Scagliotti
Oct 20, 2005·The British Journal of Ophthalmology·M T MagoneT P Margolis
Sep 8, 2011·Oman Journal of Ophthalmology·Shreya Thatte
May 29, 2012·National Journal of Maxillofacial Surgery·Sidhartha Nanda Inamuddin
May 29, 2009·Eye & Contact Lens·Gowri PachigollaV Vinod Mootha
Sep 1, 2013·Asia-Pacific Journal of Ophthalmology·Hsin-Chiung LinJu-Hsin Chia
Jul 28, 2013·Archivos de la Sociedad Española de Oftalmología·A M GuadillaM Merino
Apr 18, 2008·The Ocular Surface·Darren G Gregory
Feb 16, 2010·Experimental Eye Research·Kristyna BrejchovaKaterina Jirsova
Aug 23, 2008·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Akira KobayashiScheffer C G Tseng
Nov 12, 2015·Cornea·Mário Genilhu Bomfim PereiraLaila Christina Silveira
Sep 24, 2005·Veterinary Ophthalmology·Mary E LassalineKirk N Gelatt
Oct 14, 2004·Journal of Cellular Physiology·Gian Marco TosiPaolo Toti
Oct 14, 2004·Journal of Cellular Physiology·Gian Marco TosiPaolo Toti
Jun 6, 2003·Clinical & Experimental Ophthalmology·Peter M SumichDerek M Tole
Jan 21, 2009·Veterinary Ophthalmology·Joon Young KimDavid L Williams
Mar 17, 2007·Clinical & Experimental Ophthalmology·V Senthil MaharajanHarminder S Dua
Jul 14, 2011·Clinical & Experimental Ophthalmology·Charles N J McGhee, Dipika V Patel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.