Amniotic membrane transplantation for ligneous conjunctivitis in a doberman

Veterinary Ophthalmology
Louise O'LearyCaryn Plummer

Abstract

An approximately 2-year-old female Doberman Pinscher was referred for the evaluation of bilateral, chronic proliferative conjunctivitis. Ophthalmic examination revealed bilateral thick, opaque pseudomembranes originating from the conjunctivae that prevented visualization of the cornea and interior structures of the eye. Histopathological findings of biopsies of the pseudomembranes were consistent with ligneous conjunctivitis. Serum plasminogen activity levels were within the normal range. Treatment with topical and systemic anti-inflammatory and immunosuppressive drugs did not improve the conjunctival lesions. The pseudomembranes were surgically excised, and the conjunctival surfaces were reconstructed with amniotic membrane. At final re-examination two years postsurgery, there was no evidence of recurrence of the pseudomembranes. To the authors' knowledge, this is the first reported case of the successful treatment of canine ligneous conjunctivitis with amniotic membrane transplantation.

References

Jul 25, 1991·American Journal of Ophthalmology·B I RubinR B Nussenblatt
Feb 15, 1989·American Journal of Ophthalmology·E J HollandR B Nussenblatt
Aug 1, 1987·Ophthalmology·A A Hidayat, P J Riddle
Sep 1, 1996·Journal of the American Animal Hospital Association·D T RamseyJ A Render
Nov 1, 1995·Ophthalmology·R De CockP Wright
Dec 24, 1997·American Journal of Ophthalmology·S C TsengS H Lee
Mar 7, 2000·Inflammation·M L RamsbyG S Makowski
Oct 25, 2000·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·J KraftV Schuster
Apr 5, 2002·American Journal of Ophthalmology·Patrick WattsDavid Rootman
Jul 10, 2003·Survey of Ophthalmology·Volker Schuster, Stefan Seregard
Aug 4, 2004·American Journal of Ophthalmology·Khalid F Tabbara
May 25, 2005·Veterinary Ophthalmology·Paulo S M BarrosDennis E Brooks
May 13, 2006·Journal of Thrombosis and Haemostasis : JTH·N LaurensM P M de Maat
Aug 19, 2007·Virchows Archiv : an International Journal of Pathology·M Teresa Rodríguez-AresJosé Cameselle-Teijeiro
Mar 4, 2008·Journal of the American Veterinary Medical Association·Nancy S Johnstone McLeanMarcia R S Ilha
May 1, 2008·European Cells & Materials·Hassan NiknejadAlexander M Seifalian
Jul 17, 2009·Veterinary Ophthalmology·María-Dolores TorresTeresa Peña
Sep 18, 2009·Veterinary Research Communications·Marissak KalpravidhSudson Sirivaidyapong
Oct 21, 2009·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Nadia AzadAyesha Khan
Sep 3, 2011·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Mandira HiremathPaul Monagle
Dec 4, 2012·Indian Journal of Ophthalmology·Ozlem Yalcin TokFirdevs Ornek

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.