PMID: 41735Jan 1, 1979

Amphotericin B induced structural changes of the erythrocyte membrane

Experimentelle Pathologie
H W Meyer


Incubation of human erythrocytes in isotonic NaCl-sucrose medium with a relative high concentration of amphotericin B results in the occurrence of distinct structures on the membrane faces as visible by freeze-fracturing. Such kind of structures is known to be formed by phase separation of the lipid components (domain formation). The induction of phase separation is considered to be an additional effect of amphotericin B.


Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·H A Chapman, J B Hibbs
Feb 6, 1976·Biochimica Et Biophysica Acta·U B SleytrK J Thorne
Oct 3, 1975·Science·D BrantonR S Weinstein

Related Concepts

Injection, Amphotericin B,50 MG Administered
Amphotericin B Colloidal Dispersion
Specimen Type - Erythrocytes
Freeze Fracturing
Sodium Chloride
Red Blood Cell Count Measurement
Erythrocyte Membrane
Red Cell Ghost

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