PMID: 9431923Feb 12, 1998Paper

Amplification of ehrlichial DNA from dogs 34 months after infection with Ehrlichia canis

Journal of Clinical Microbiology
S HarrusH Bark

Abstract

In order to determine whether dogs in the subclinical phase of canine monocytic ehrlichiosis (CME) are carriers of Ehrlichia canis and to determine the significance of persistent indirect immunofluorescent anti-E. canis antibody titers during this phase, PCR was performed with blood, bone marrow, and splenic aspirates collected 34 months postinoculation from six clinically healthy beagle dogs experimentally infected with E. canis. At least one of the three samples (spleen, bone marrow, and blood) from four of the six dogs was PCR positive. The spleens of all four of these dogs were PCR positive, and the bone marrow and blood of two of the four dogs were PCR positive. Indirect immunofluorescent-antibody titers increased progressively during the first 5 months postinfection, remained high for an additional period of more than 11 months, and declined thereafter, suggesting that the dogs were recovering from the disease. Five of the dogs remained seropositive 34 months postinfection. The data obtained in this study demonstrate for the first time that clinically healthy dogs in the subclinical phase of CME are carriers of the rickettsia. It was shown that dogs can harbor E. canis for years without developing the chronic clinical dis...Continue Reading

References

Dec 1, 1991·Journal of Clinical Microbiology·B E AndersonK H Wilson
Mar 1, 1994·Journal of Clinical Microbiology·S M ChenD H Walker
Nov 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J S DumlerD H Walker
Mar 16, 1996·The Veterinary Record·G BanethA Keysary

❮ Previous
Next ❯

Citations

Jul 16, 2003·Annals of the New York Academy of Sciences·Miroslav PetrovecGilda Wüst
Oct 9, 2003·Journal of Medical Microbiology·Xiao-Feng ZhangXue-Jie Yu
Jun 21, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Raphael B Stricker
Jan 6, 2009·Annals of the New York Academy of Sciences·Enara AguirreAngel Sainz
May 28, 2009·Vector Borne and Zoonotic Diseases·Pedro Paulo V P DinizEdward B Breitschwerdt
Apr 14, 2010·Journal of Veterinary Internal Medicine·M E MylonakisA F Koutinas
Oct 6, 2010·Antimicrobial Agents and Chemotherapy·Jennifer C McClureRoger W Stich
Oct 2, 2012·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·L D SinglaP D Juyal
Oct 22, 2013·Veterinary Clinical Pathology·Salah Al IzziChristian M Leutenegger
Oct 3, 2014·Journal of Veterinary Internal Medicine·M Lanza-PereaE B Breitschwerdt
May 8, 2004·Journal of the American Animal Hospital Association·Mathios E MylonakisVassilios S Kontos
Apr 22, 2003·Infection and Immunity·Jere W McBrideDavid H Walker
Jun 20, 2008·Journal of Veterinary Internal Medicine·T A PetanidesS Lekkas
Mar 12, 2013·The Journal of Antimicrobial Chemotherapy·Konstantina TheodorouShimon Harrus
Feb 5, 2015·Parasites & Vectors·Ángel SainzLaia Solano-Gallego
Jun 18, 2015·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Paula Elisa Brandão GuedesFabiana Lessa Silva
Feb 24, 2001·Annals of the New York Academy of Sciences·I KakomaM G Levy
May 28, 2005·Expert Review of Anti-infective Therapy·Raphael B StrickerJoseph J Burrascano
Jul 4, 2007·Antimicrobial Agents and Chemotherapy·John J SchaeferR W Stich
Jul 6, 2004·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Dagmar HulínskáIvan Pavlásek
Nov 28, 2012·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Felipe da Silva KrawczakSônia Terezinha Dos Anjos Lopes
Mar 29, 2011·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Rafael Felipe da Costa VieiraOdilon Vidotto
Sep 9, 2010·Expert Review of Vaccines·Jere W McBride, David H Walker
Mar 29, 2011·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Joice Lara Maia FariaMirela Tinucci-Costa
Feb 25, 2006·Chemotherapy·Raphael B StrickerJoseph J Burrascano
Mar 5, 2015·The Journal of Infectious Diseases·Tais Berelli Saito, David H Walker
Aug 31, 2016·Veterinary Sciences·Tais B Saito, David H Walker
Jul 23, 2003·Journal of the American Animal Hospital Association·Heather L HeebRoman Reddy Ganta
Nov 22, 2012·Vector Borne and Zoonotic Diseases·Dennis R BellSusan Sanchez
Jul 27, 2001·The Veterinary Record·Y SutoT Hayashi
Feb 7, 2018·Veterinary Clinical Pathology·Itamar ArochOrit Chai
Sep 15, 2017·Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·Jacqueline CsokaiElisabeth Müller
Sep 17, 2019·Comparative Immunology, Microbiology and Infectious Diseases·Melina M Ojeda-ChiSandra L Villegas-Perez
Apr 13, 1999·Biochemical and Biophysical Research Communications·C R SulsonaA F Barbet

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.