PMID: 3765514Jan 1, 1986Paper

Amplification of myc-specific sequences in human colonic cancer

Voprosy onkologii
O M SerovaL B Novikov

Abstract

DNA samples obtained from tumors and adjacent mucosa of the large bowel of a patient with large bowel multiple neoplasia were examined after Southern. The procedure established amplification of v-myc oncogene-related DNA sequences in 1 out of 5 tumors tested. Restriction fragments of amplified myc-specific sequences and matching c-myc and N-myc loci of the human genome differed in size.

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