Oct 29, 2004

Amplitude spectrum area: measuring the probability of successful defibrillation as applied to human data

Critical Care Medicine
Clayton YoungMax Harry Weil


The objective of our study was to examine the effectiveness of an electrocardiographic predictor, amplitude spectral area (AMSA), for the optimal timing of defibrillation shocks in human victims of cardiac arrest. Based on the spectral characteristics of ventricular fibrillation potentials, we examined the probability of successful conversion to an organized viable rhythm, including the return of spontaneous circulation. The incentive was to predict the likelihood of successful defibrillation and thereby improve outcomes by minimizing interruptions in chest compression and minimizing electrically induced myocardial injury due to repetitive high-current shocks. Observational study on human electrocardiographic recordings during cardiopulmonary resuscitation. Medical research laboratory of a university-affiliated research and educational institute. Victims of out-of-hospital cardiac arrest. Iteration of electrocardiographic records, representing lead 2 equivalent recordings on 108 defibrillation attempts with an automated external defibrillator, of 46 victims of cardiac arrest due to ventricular fibrillation. Three seconds of ventricular fibrillation, recorded immediately preceding delivery of a shock, were analyzed utilizing the...Continue Reading

Mentioned in this Paper

Ventricular Fibrillation
Anterior Thoracic Region
Observation - Diagnostic Procedure

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