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Amrinone reduces pulmonary vascular resistance elevated by U46619 in isolated perfused lungs

Journal of Cardiovascular Pharmacology

Jul 1, 1991

William P ClarkeL O Soltow

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Abstract

The effects of amrinone on pulmonary vascular resistance (PVR) were studied in an isolated, perfused rabbit lung model where all the major determinants of PVR were controlled. In this preparation, the alveolar oxygen and carbon dioxide tensions, vascular pH and vascular oxygen and carbo...read more

Mentioned in this Paper

15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Perfusion
Blood Gas Analysis
Prostaglandin Endoperoxides, Synthetic
Alveolar
Blood Vessel
Dose-Response Relationship, Drug
Thromboxane A2
Metazoa
Oxygen Consumption

Amrinone reduces pulmonary vascular resistance elevated by U46619 in isolated perfused lungs

Journal of Cardiovascular Pharmacology

Jul 1, 1991

William P ClarkeL O Soltow

PMID: 1719296

DOI: 10.1097/00005344-199107000-00012

Abstract

The effects of amrinone on pulmonary vascular resistance (PVR) were studied in an isolated, perfused rabbit lung model where all the major determinants of PVR were controlled. In this preparation, the alveolar oxygen and carbon dioxide tensions, vascular pH and vascular oxygen and carbo...read more

Mentioned in this Paper

15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Perfusion
Blood Gas Analysis
Prostaglandin Endoperoxides, Synthetic
Alveolar

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