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Amyloid-β Positivity Predicts Cognitive Decline but Cognition Predicts Progression to Amyloid-β Positivity

Biological Psychiatry

Feb 19, 2020

Jeremy A ElmanAlzheimer’s Disease Neuroimaging Initiative

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PubMed

Abstract

Stage 1 of the National Institute on Aging-Alzheimer's Association's proposed Alzheimer's disease continuum is defined as amyloid-β (Aβ) positive but cognitively normal. Identifying at-risk individuals before Aβ reaches pathological levels could have great benefits for early interventio...read more

Mentioned in this Paper

Pathology
Participant
Phosphorylation
Cognition
United States National Institutes of Health
Biological Markers
Follow-up
Cerebrospinal Fluid
Pre-Clinical Model
Survival Analysis
2
14
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Amyloid-β Positivity Predicts Cognitive Decline but Cognition Predicts Progression to Amyloid-β Positivity

Biological Psychiatry

Feb 19, 2020

Jeremy A ElmanAlzheimer’s Disease Neuroimaging Initiative

PMID: 32067693

DOI: 10.1016/j.biopsych.2019.12.021

Abstract

Stage 1 of the National Institute on Aging-Alzheimer's Association's proposed Alzheimer's disease continuum is defined as amyloid-β (Aβ) positive but cognitively normal. Identifying at-risk individuals before Aβ reaches pathological levels could have great benefits for early interventio...read more

Mentioned in this Paper

Pathology
Participant
Phosphorylation
Cognition
United States National Institutes of Health
Biological Markers
Follow-up
Cerebrospinal Fluid
Pre-Clinical Model
Survival Analysis
2
14

Feeds With Similar Papers

Tau Aggregation: Genomics

Tau Aggregation is an important characteristic in some neurodegenerative disorders, including Alzheimer’s Disease. Discover the latest research using genomics to understand Tau Aggregation.

Tauopathies

Tauopathies are neurodegenerative disorders caused due to misfolding and aggregation of the tau protein in neurofibrillary tangles in the brain. Discover the latest research on tauopathies here.

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CSF biomarker and PIB-PET-derived beta-amyloid signature predicts metabolic, gray matter, and cognitive changes in nondemented subjects

Cerebral CortexNovember 1, 2011
Michael EwersAlzheimer’s Disease Neuroimaging Initiative (ADNI)
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