Amyloid arthropathy mimicking seronegative rheumatoid arthritis in multiple myeloma: case reports and review of the literature

Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis
Nilüfer AlpaySevgi Kalayoğlu-Beşişik

Abstract

We report two patients who suffered from symmetrical polyarthritis simulating rheumatoid arthritis. Acute phase response was almost within normal limits, and autoantibodies including rheumatoid factor were negative. Both of them were diagnosed as having amyloid arthropathy (AmyA) secondary to kappa multiple myeloma based on deposition of kappa-light chain-immunoreactive amyloid in biopsied tissue and Bence Jones protein in urine. Systemic AL amyloidosis may be important in the differential diagnosis of chronic polyarthralgia.

References

Nov 1, 1972·Medicine·P H Wiernik
Feb 15, 1973·The New England Journal of Medicine·G A KatzW S Adams
Nov 1, 1984·The American Journal of Medicine·K N LaiD Yeung
Feb 1, 1996·Rheumatic Diseases Clinics of North America·G F Duna, J M Cash
Jun 12, 2002·Current Treatment Options in Oncology·R L Comenzo
Nov 1, 2003·Seminars in Musculoskeletal Radiology·Patrick J Sheldon, Deborah M Forrester
Apr 28, 2004·La Revue de médecine interne·S HamzaS Sellami
Oct 6, 2006·American Journal of Hematology·Mohammad Reza Ardalan, Mohammadali Mohajel Shoja
Mar 14, 2007·Joint, Bone, Spine : Revue Du Rhumatisme·Fahri SahinYesim Ertan
Oct 31, 2007·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·Gulistan BahatNesimi Buyukbabani
Dec 29, 2007·British Journal of Haematology·Ashutosh D WechalekarJulian D Gillmore
Jun 17, 2008·Internal Medicine·Nagaaki KatohShu-ichi Ikeda

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Citations

Jun 24, 2011·Clinical Rheumatology·Vinod Ravindran, Parameswaran Anoop
Sep 3, 2013·Seminars in Arthritis and Rheumatism·Ahmed M ElsamanFrank Pessler
Aug 16, 2016·International Journal of Rheumatic Diseases·Sukesh EdavalathAble Lawrence
Nov 9, 2018·Case Reports in Rheumatology·Scott SchoningerNatasa Milojkvovic
Jul 20, 2018·Rheumatology International·Gil BornsteinChagai Grossman
Sep 6, 2019·JAMA : the Journal of the American Medical Association·Abdullah S Al SalehMorie A Gertz
Dec 4, 2020·Modern Rheumatology Case Reports·Muhammad Shoaib Momen MajumderJohannes J Rasker

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