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Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease

Frontiers in Neurology

Nov 1, 2019

Yu DingYuesong Gong

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Abstract

Introduction: β-Amyloid protein (Aβ) putatively plays a seminal role in synaptic loss in Alzheimer's disease (AD). While there is no consensus regarding the synaptic-relevant species of Aβ, it is known that Aβ oligomers (AβOs) are noticeably increased in the early stages of AD, localizi...read more

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Na(+)-K(+)-Exchanging ATPase
Aging
Alzheimer's Disease
Western Blotting
High Pressure Liquid Chromatography Procedure
Frontal Lobe
Neurons
Synapses
Ultracentrifugation
Postsynaptic density proteins
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2
2
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Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease

Frontiers in Neurology

Nov 1, 2019

Yu DingYuesong Gong

PMID: 31736856

DOI: 10.3389/fneur.2019.01140

Abstract

Introduction: β-Amyloid protein (Aβ) putatively plays a seminal role in synaptic loss in Alzheimer's disease (AD). While there is no consensus regarding the synaptic-relevant species of Aβ, it is known that Aβ oligomers (AβOs) are noticeably increased in the early stages of AD, localizi...read more

Mentioned in this Paper

Na(+)-K(+)-Exchanging ATPase
Aging
Alzheimer's Disease
Western Blotting
High Pressure Liquid Chromatography Procedure
5
2
2

Similar Papers Found In These Feeds

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