journal cover

Amyloid Oligomers, Protofibrils and Fibrils

Sub-cellular Biochemistry

Jan 16, 2020

Mohammad Khursheed SiddiqiRizwan Hasan Khan

Abstract

Amyloid diseases are of major concern all over the world due to a number of factors including: (i) aging population, (ii) increasing life span and (iii) lack of effective pharmacotherapy options. The past decade has seen intense research in discovering disease-modifying multi-targeting ...read more

Mentioned in this Paper

Neurotoxicity Syndromes
Species
Amyloidosis
Small Molecule
Pharmacotherapy
Gradual Progression
Aging
Fibril - Cell Component
Research
PGE1 oligomer
1
1
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Neurotoxicity, Inflammation & Neuroprotection

The end result of the inflammatory process, neurotoxicity and/or neuroprotection, is a function of the fine balance between the two cellular systems, i.e., of the complex signaling relationships between anti-inflammatory neuroprotective factors (neurotrophins and other chemical mediators) and proinflammatory neurotoxic factors (tnf, free radicals, certain cytokines, etc). Here are the latest discoveries pertaining to neurotoxicity, inflammation and neuroprotection.

Decision Making & Cognitive Aging

While abilities like vocabulary resist aging, other abilities such as memory, decision-making, and reasoning, gradually decline. Here is the latest research on decision-making and cognitive aging.

Cell Aging

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Drug & Digital Interventions

This feed describes how digital interventions, which are digital and mobile technologies used to support health system needs, can complement and improve pharmacotherapy in disease management. Discover the latest research on drug and digtial intervention here,

Aging Epidemiology

This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.

Age-related Dementia

Age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the neuropathology of the dementia is caused by the breakdown of small cerebral vessels (silent microbleeds), that the microbleeds result from pulse-induced damage to the cerebral vessels, and that pulse becomes increasingly destructive with age, because of the age-related stiffening of the aorta and great arteries, which causes an increase in the intensity of the pressure pulse. Discover the latest research on age-related dementia here.

Aging Epidemiology

This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.

Cell Aging (Keystone)

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Related Papers

European Journal of Medicinal Chemistry

Amyloid cascade in Alzheimer's disease: Recent advances in medicinal chemistry

European Journal of Medicinal ChemistryMarch 6, 2016
Tarek MohamedPraveen P N Rao
Advances in Protein Chemistry and Structural Biology

Cytotoxic species in amyloid-associated diseases: Oligomers or mature fibrils

Advances in Protein Chemistry and Structural BiologyJanuary 14, 2020
Mohammad Khursheed SiddiqiRizwan Hasan Khan
© 2020 Meta ULC. All rights reserved

Amyloid Oligomers, Protofibrils and Fibrils

Sub-cellular Biochemistry

Jan 16, 2020

Mohammad Khursheed SiddiqiRizwan Hasan Khan

PMID: 31939162

DOI: 10.1007/978-3-030-28151-9_16

Abstract

Amyloid diseases are of major concern all over the world due to a number of factors including: (i) aging population, (ii) increasing life span and (iii) lack of effective pharmacotherapy options. The past decade has seen intense research in discovering disease-modifying multi-targeting ...read more

Mentioned in this Paper

Neurotoxicity Syndromes
Species
Amyloidosis
Small Molecule
Pharmacotherapy
Gradual Progression
Aging
Fibril - Cell Component
Research
PGE1 oligomer
1
1

Similar Papers Found In These Feeds

Neurotoxicity, Inflammation & Neuroprotection

The end result of the inflammatory process, neurotoxicity and/or neuroprotection, is a function of the fine balance between the two cellular systems, i.e., of the complex signaling relationships between anti-inflammatory neuroprotective factors (neurotrophins and other chemical mediators) and proinflammatory neurotoxic factors (tnf, free radicals, certain cytokines, etc). Here are the latest discoveries pertaining to neurotoxicity, inflammation and neuroprotection.

Decision Making & Cognitive Aging

While abilities like vocabulary resist aging, other abilities such as memory, decision-making, and reasoning, gradually decline. Here is the latest research on decision-making and cognitive aging.

Related Papers

European Journal of Medicinal Chemistry

Amyloid cascade in Alzheimer's disease: Recent advances in medicinal chemistry

European Journal of Medicinal ChemistryMarch 6, 2016
Tarek MohamedPraveen P N Rao
Advances in Protein Chemistry and Structural Biology

Cytotoxic species in amyloid-associated diseases: Oligomers or mature fibrils

Advances in Protein Chemistry and Structural BiologyJanuary 14, 2020
Mohammad Khursheed SiddiqiRizwan Hasan Khan
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/amyloid-oligomers-protofibrils-and/31939162