PMID: 49034Jun 1, 1975Paper

Amyloidosis: a rational approach to diagnosis by intraoral biopsy

Oral Surgery, Oral Medicine, and Oral Pathology
H C Schwartz, D J Olson

Abstract

Amyloidosis and its oral manifestations are briefly described. The techniques for antemortem tissue diagnosis of amyloidosis are reviewed and evaluated. In screening for amyloidosis, biopsy of specific oral lesions (when present) is recommended instead of the traditional biopsy of normal-appearing gingiva. This approach is illustrated with four cases. Although rectal biopsy is generally accepted as the screening technique of choice, it is suggested that intraoral biopsy be considered as an easier, safer, more comfortable, and possibly more fruitful technique. It is advocated that in cases of both documented and suspected amyloidosis both intraoral and rectal biopsies should be performed in order to help provide documentation of the most useful technique for routine screening.

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Citations

Apr 15, 1997·Journal of the Neurological Sciences·J FinstererB Mamoli
Dec 29, 2015·The British Journal of Oral & Maxillofacial Surgery·Robert Stuart McCormickMarco Carrozzo
Apr 1, 1990·Clinics in Dermatology·C K Wong
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Nov 1, 1988·Journal of Oral Pathology·E J RaubenheimerF J Pretorius
May 1, 1987·Journal of Oral Pathology·Y TakedaH Hirose
Jan 1, 1977·Oral Surgery, Oral Medicine, and Oral Pathology·R A KrautA Acevedo
Aug 21, 2019·Liver International : Official Journal of the International Association for the Study of the Liver·Yue-Can ZengYu-Hong Zhao

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