An account of the real-life hepatitis C management in a single specialized viral hepatitis treatment centre in Egypt: results of treating 7042 patients with 7 different direct acting antiviral regimens

Expert Review of Gastroenterology & Hepatology
M El KassasGamal Esmat

Abstract

A large Egyptian treatment program for HCV was launched in2014 after the introduction of direct-acting antiviral agents (DAAs). This program depended mainly on establishing specialized independent centres for HCV treatment. These centres represent the major strengths in the Egyptian model of care, as they provide integrated care for HCV patients and have enabled Egypt to treat more than one million patients in 3 years. The New Cairo Viral Hepatitis Treatment Center (NCVHTC) is an example of these specialized centres. The Egyptian experience in the management of HCV was evaluated by analysing the data of real-life HCV management in the NCVHTC from 2014 to 2017. Results of different treatment regimens in addition to their strengths, limitations and areas for improvement are discussed in this report. A total of 7042 HCV patients have been evaluated for treatment in the NCVHTC. Among them, 5517 patients received treatment by seven different DAA regimens with excellent results. All regimens were highly effective at treating HCV in a real-life setting, apart from SOF/RBV, which was the least effective. A nationwide screening program and enhancing the follow-up of treated patients are the main missing pillars in the Egyptian model.

References

Nov 23, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Khayriyyah Mohd HanafiahSteven T Wiersma
Jul 30, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jane P MessinaEleanor Barnes
May 6, 2015·Journal of Hepatology·Wahid DossGamal Esmat
Sep 24, 2016·Expert Opinion on Drug Safety·Mohamed El KassasGamal Esmat
Nov 5, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Rasha EletrebyGamal Esmat
Jan 11, 2017·Alimentary Pharmacology & Therapeutics·A ElsharkawyG Esmat
May 10, 2017·Expert Review of Gastroenterology & Hepatology·Aisha ElsharkawyGamal Esmat
Aug 5, 2017·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Tamer ElbazGamal Esmat
Mar 7, 2018·Expert Review of Anti-infective Therapy·Mohamed El KassasGamal Esmat

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Citations

Oct 23, 2018·World Journal of Gastroenterology : WJG·Dalia OmranMohamed El Kassas
Mar 11, 2021·Current Medical Research and Opinion·Mohamed El KassasAhmed Hosny
Apr 7, 2021·Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology·Arwa KamhawyGamal Esmat
May 16, 2021·Microbiology and Immunology·Ashraf ElbahrawyHussein Hassan Aly

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