An Acute Adverse Reaction with ST Elevation Induced by Magnetic Resonance Contrast Media: Kounis Syndrome

Internal Medicine
Hiroki TanakaMakoto Takenaga

Abstract

A 78-year-old man with mild coronary arteriosclerosis on coronary CT angiography underwent MRI of the prostate with the administration of Gadolinium-based contrast agent (GBCA) (gadopentetate dimeglumine). He developed acute coronary syndrome immediately after the intravenous injection of GBCA, and recovered after the administration of nitroglycerine, atropine sulfate, and hydrocortisone. He was discharged on the ninth day of hospitalization without recurrent chest symptoms. This is the second reported case of Kounis syndrome caused by GBCA. Kounis syndrome caused by MR contrast media is rare, but we should recognize that all contrast agents have the potential to cause Kounis syndrome.

References

Feb 28, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A HelblingW J Pichler
Jan 25, 2011·AJR. American Journal of Roentgenology·Martin R PrincePaula W Brill
Nov 5, 2011·Future Cardiology·Nicholas G KounisJohn Goudevenos
May 3, 2012·Radiology·Jae-Woo JungSang-Heon Cho
Oct 11, 2012·Polish journal of radiology·Tomasz Kun, Lucjusz Jakubowski
Jul 15, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·O BruderH Mahrholdt
Oct 30, 2015·International Journal of Cardiology·Francesca RendaLuca Pani
Mar 12, 2016·Clinical Chemistry and Laboratory Medicine : CCLM·Nicholas G Kounis

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Citations

Jul 18, 2020·Proceedings·Nicholas G KounisGeorge Hahalis
Jun 14, 2019·Proceedings·Waiel AbusninaFuad Zeid

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