PMID: 6978840Jan 1, 1981Paper

An acute lymphoblastic leukemia which produces human T cell growth factor

Immunological Communications
D W AndersonC Jones

Abstract

We report the production of T cell growth factor activity by a PHA stimulated acute lymphoblastic leukemia cell line designated HSB-2. Factor production was enhanced by the addition of phorbol myristate acetate to the cultures. The growth factor will enhance the proliferation of PHA stimulated thymocytes and sustain the proliferation of growth-factor dependent human T cell blasts. The characteristics of the cell line are described.

References

May 28, 1981·Nature·C S HenneyS Gillis
Mar 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·E L ReinherzS F Schlossman
Jan 1, 1980·Immunological Reviews·K A Smith
Jan 1, 1981·Infection and Immunity·A J Crowle, M May

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