An adaptive MR-CT registration method for MRI-guided prostate cancer radiotherapy

Physics in Medicine and Biology
Hualiang ZhongIndrin J Chetty

Abstract

Magnetic Resonance images (MRI) have superior soft tissue contrast compared with CT images. Therefore, MRI might be a better imaging modality to differentiate the prostate from surrounding normal organs. Methods to accurately register MRI to simulation CT images are essential, as we transition the use of MRI into the routine clinic setting. In this study, we present a finite element method (FEM) to improve the performance of a commercially available, B-spline-based registration algorithm in the prostate region. Specifically, prostate contours were delineated independently on ten MRI and CT images using the Eclipse treatment planning system. Each pair of MRI and CT images was registered with the B-spline-based algorithm implemented in the VelocityAI system. A bounding box that contains the prostate volume in the CT image was selected and partitioned into a tetrahedral mesh. An adaptive finite element method was then developed to adjust the displacement vector fields (DVFs) of the B-spline-based registrations within the box. The B-spline and FEM-based registrations were evaluated based on the variations of prostate volume and tumor centroid, the unbalanced energy of the generated DVFs, and the clarity of the reconstructed anatomi...Continue Reading

References

Jul 15, 1996·International Journal of Radiation Oncology, Biology, Physics·M RoachH Hricak
Jun 1, 1997·IEEE Transactions on Medical Imaging·M H DavisS E Harms
Feb 16, 1999·International Journal of Radiation Oncology, Biology, Physics·R J AmdurR D Harris
Apr 22, 2003·Annual Review of Biomedical Engineering·James F GreenleafMichael Insana
Aug 9, 2003·IEEE Transactions on Medical Imaging·Josien P W PluimMax A Viergever
Dec 14, 2004·International Journal of Radiation Oncology, Biology, Physics·Alfredo PoloRoberto Orecchia
Dec 21, 2004·Magnetic Resonance Imaging·Deming WangRichard Slaughter
May 14, 2005·International Journal of Radiation Oncology, Biology, Physics·Eduard Schreibmann, Lei Xing
Jul 5, 2005·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Geert M VilleirsGert O De Meerleer
Oct 4, 2005·International Journal of Radiation Oncology, Biology, Physics·John M SchallenkampThomas M Pisansky
Oct 11, 2005·Computer Methods in Biomechanics and Biomedical Engineering·Hualiang ZhongTerry M Peters
May 16, 2006·Medical Physics·Eduard Schreibmann, Lei Xing
Aug 3, 2007·Physics in Medicine and Biology·Hualiang ZhongJeffrey V Siebers
Sep 11, 2009·Physics in Medicine and Biology·Hualiang Zhong, Jeffrey V Siebers
Nov 20, 2009·IEEE Transactions on Medical Imaging·Stefan KleinJosien P W Pluim
Feb 23, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jonathan LambertOlivier Salvado
Oct 1, 2011·Journal of Radiation Research·Hidekazu TanakaTakayoshi Iida
May 15, 2012·Physics in Medicine and Biology·Hualiang ZhongIndrin J Chetty
May 31, 2013·Medical Physics·Anne Sofie KorsagerLasse Riis Østergaard
Sep 5, 2013·Physics in Medicine and Biology·Shunshan LiHualiang Zhong

❮ Previous
Next ❯

Citations

Jul 15, 2015·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Tiina SeppäläKauko Saarilahti
Jan 24, 2017·Physics in Medicine and Biology·Kim Melanie KrausAsja Pfaffenberger
Aug 3, 2020·Journal of Medical Radiation Sciences·Jeffrey BarberDavid Thwaites
Sep 10, 2016·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Ashesh B JaniDavid M Schuster
Sep 11, 2021·Journal of Radiation Research·Tomoya IshidaKeiichi Jingu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.