PMID: 9525768Apr 3, 1998Paper

An admissible solution approach to inverse electrocardiography

Annals of Biomedical Engineering
G F AhmadR S MacLeod

Abstract

The goal of the inverse problem of electrocardiography is noninvasive discrimination and characterization of normal/abnormal cardiac electrical activity from measurements of body surface potentials. Smoothing and attenuation in the torso volume conductor cause the problem to be ill posed. Standard regularized solutions employ an a priori constraint to achieve reliability and may be biased by the constraint chosen as well as the regularization parameter used to weight it. In this paper, we describe an approach that reformulates this inverse problem as the search for a solution that is a member of an admissible solution set; admissibility is defined in terms of the available constraints. In principle, this approach can utilize as many constraints as may be available, unlike standard techniques which do not easily permit the use of multiple constraints. No regularization parameter is required; instead, we need to choose the nature and size of the constraint sets. Constraints described include several spatial constraints, weighted constraints, and temporal constraints. We describe a solution approach based on iterative convex optimization, and the algorithm--the ellipsoid algorithm--which we have used. Accuracy and feasibility of t...Continue Reading

Citations

Dec 12, 2012·Medical & Biological Engineering & Computing·Yesim Serinagaoglu Dogrusoz, Alireza Mazloumi Gavgani
Feb 14, 1998·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·R S MacLeod, D H Brooks
Mar 9, 2011·IEEE Transactions on Bio-medical Engineering·Dafang WangChris R Johnson
Sep 21, 2004·IEEE Transactions on Bio-medical Engineering·Bernd MessnarzBernhard Tilg
Oct 15, 1998·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·R M Gulrajani
Feb 10, 2004·IEEE Transactions on Bio-medical Engineering·Bernd MessnarzFriedrich Hanser
Sep 7, 2002·IEEE Transactions on Bio-medical Engineering·R D ThroneJ R Windle
Apr 14, 2000·IEEE Transactions on Bio-medical Engineering·R D Throne, L G Olson
Aug 1, 2019·Medical & Biological Engineering & Computing·Taha Erenler, Yesim Serinagaoglu Dogrusoz
Oct 24, 1998·Progress in Biophysics and Molecular Biology·C R Johnson, R S MacLeod

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