Abstract
Until now, the prevalence of macrolide-resistant Mycoplasma pneumoniae (MP) infection among adult patients has been low, and severe MP pneumonia due to a macrolide-resistant strain has seldom been reported. Here, we describe a rare case of severe life-threatening MP pneumonia due to a macrolide-resistant strain in an adult, which was finally treated with fluoroquinolone and tetracycline after failed treatment with macrolide and corticosteroid. A 39-year-old apparently healthy woman complained of fever and productive cough. Three days after onset, she was admitted to a local general hospital. On admission, her vital signs were stable except for high-grade fever. The patient's chest X-ray and chest computed tomography images revealed subsegmental consolidation in her right lower lobe. Treatment with ampicillin/sulbactam, and azithromycin were initiated under a clinical diagnosis of community-acquired pneumonia. After treatment initiation, her fever had not subsided, and the pulmonary lesion had extended to the entire lower lobe. Thus, treatment with prednisolone as steroid pulse therapy was initiated from clinical day 7. However, neither her symptoms nor her pulmonary lesion improved; therefore, she was transferred to our hospita...Continue Reading
References
Mar 7, 2001·Journal of Clinical Microbiology·J W Dorigo-ZetsmaJ M van den Bosch
Nov 25, 2004·Antimicrobial Agents and Chemotherapy·Mayumi MatsuokaTsuguo Sasaki
Feb 17, 2005·Journal of Medical Microbiology·Riitta RätyMarjaana Kleemola
Sep 21, 2007·Journal of Clinical Microbiology·S PereyreC M Bébéar
Nov 24, 2007·Journal of Medical Microbiology·Naoyuki MiyashitaMikio Oka
Jul 11, 2008·Journal of Clinical Microbiology·Jonas M WinchellBarry S Fields
Apr 1, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kathleen A ThurmanJonas M Winchell
Jul 28, 2009·The Pediatric Infectious Disease Journal·Xiao LiKen B Waites
Aug 3, 2010·International Journal of Antimicrobial Agents·Naoyuki MiyashitaKazunobu Ouchi
Mar 26, 2011·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Mitsuo Narita
Sep 6, 2012·Pediatric Pulmonology·Yuelin ShenKunling Shen
Nov 22, 2012·The Journal of Antimicrobial Chemotherapy·Nicola Principi, Susanna Esposito
Mar 6, 2013·Antimicrobial Agents and Chemotherapy·Yasuhiro KawaiKazunobu Ouchi
May 30, 2013·Antimicrobial Agents and Chemotherapy·Yasuhiro KawaiKazunobu Ouchi
Jul 31, 2013·Antimicrobial Agents and Chemotherapy·Naoyuki MiyashitaNiro Okimoto
Aug 24, 2013·Emerging Infectious Diseases·AliReza EshaghiSamir N Patel
Jan 28, 2014·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Koichi IzumikawaShigeru Kohno
Dec 24, 2014·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Naoyuki MiyashitaNiro Okimoto
Mar 20, 2016·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Naoyuki MiyashitaNiro Okimoto
Nov 14, 2018·Case Reports in Critical Care·Naoki KawakamiHideki Yuki
Citations
Aug 22, 2020·Journal of Chemotherapy·Md Moinuddin SheamSudhangshu Kumar Biswas
May 26, 2020·BMC Infectious Diseases·Lin DingHangyong He
Jul 16, 2020·Medicine·Xin YuanYuan Luo
May 14, 2021·Internal and Emergency Medicine·Naoto IshimaruTetsuhiro Maeno