An Algorithm for Real-Time Pulse Waveform Segmentation and Artifact Detection in Photoplethysmograms

IEEE Journal of Biomedical and Health Informatics
Christoph FischerThomas Penzel

Abstract

Photoplethysmography has been used in a wide range of medical devices for measuring oxygen saturation, cardiac output, assessing autonomic function, and detecting peripheral vascular disease. Artifacts can render the photoplethysmogram (PPG) useless. Thus, algorithms capable of identifying artifacts are critically important. However, the published PPG algorithms are limited in algorithm and study design. Therefore, the authors developed a novel embedded algorithm for real-time pulse waveform (PWF) segmentation and artifact detection based on a contour analysis in the time domain. This paper provides an overview about PWF and artifact classifications, presents the developed PWF analysis, and demonstrates the implementation on a 32-bit ARM core microcontroller. The PWF analysis was validated with data records from 63 subjects acquired in a sleep laboratory, ergometry laboratory, and intensive care unit in equal parts. The output of the algorithm was compared with harmonized experts' annotations of the PPG with a total duration of 31.5 h. The algorithm achieved a beat-to-beat comparison sensitivity of 99.6%, specificity of 90.5%, precision of 98.5%, and accuracy of 98.3%. The interrater agreement expressed as Cohen's kappa coeffic...Continue Reading

References

Aug 1, 1977·Circulation·R P LewisH Boudoulas
Apr 1, 1989·Computer Methods and Programs in Biomedicine·A A KamalA J Mearns
May 1, 1986·Medical & Biological Engineering & Computing·M OkadaM Okada
May 1, 1974·Physics in Medicine and Biology·A V Challoner, C A Ramsay
Dec 1, 1970·Circulation·D Golde, L Burstin
Feb 1, 1968·Circulation·A M WeisslerC D Schoenfeld
Mar 1, 1996·Computers in Biology and Medicine·T L RuschJ E Scharf
Jan 12, 2001·Journal of the American College of Cardiology·H TanakaD R Seals
Apr 27, 2001·IEEE Transactions on Bio-medical Engineering·M J Hayes, P R Smith
Sep 7, 2002·Physiological Measurement·Rolando Hong EnríquezJosé Luis Hernández Cáceres
Feb 3, 2005·Journal of the American Medical Informatics Association : JAMIA·George Hripcsak, Adam S Rothschild
Mar 2, 2005·Journal of Neuroengineering and Rehabilitation·Yong-Sheng YanYuan-Ting Zhang
Oct 21, 2005·IEEE Transactions on Bio-medical Engineering·Mateo AboyBrahm Goldstein
Feb 28, 2006·Journal of the American Medical Informatics Association : JAMIA·Chenggang YuJaques Reifman
Mar 15, 2006·IEEE Transactions on Bio-medical Engineering·Byung S Kim, Sun K Yoo
Dec 6, 2007·Anesthesia and Analgesia·Paul D Mannheimer
Dec 6, 2007·Anesthesia and Analgesia·Michael T PettersonJohn M Graybeal
Jun 26, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Roberto SarnariNorman H Silverman
Apr 20, 1907·British Medical Journal·T Lewis
Nov 26, 2010·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Umar FarooqSeung-Hun Park
Feb 19, 2011·Physiological Measurement·J Abdul SukorN H Lovell
Jan 19, 2012·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Nandakumar SelvarajKi H Chon
Mar 1, 2012·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Kevin T SweeneySeán F McLoone
Jun 20, 2012·Current Cardiology Reviews·Mohamed Elgendi
Nov 6, 2012·Artificial Intelligence in Medicine·Marie ChanEric Campo
Feb 1, 2013·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·R CouceiroJ Muehlsteff
Feb 1, 2013·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Walter KarlenGuy Dumont
Feb 1, 2012·IEEE Transactions on Biomedical Circuits and Systems·Kejia LiBalasubramaniam Natarajan
Oct 11, 2013·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Carlos A Robles-RubioR E Kearney
Apr 25, 2014·IEEE Transactions on Bio-medical Engineering·Ya-Li ZhengYuan-Ting Zhang
Jul 30, 2014·IEEE Journal of Biomedical and Health Informatics·Christina OrphanidouLionel Tarassenko

❮ Previous
Next ❯

Citations

Dec 31, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Bo PengHaiqing Xie
Oct 26, 2018·BioMed Research International·Suyi LiDongsheng Li
Feb 23, 2020·Computational and Mathematical Methods in Medicine·Weiguang NiSuyi Li
Jun 25, 2020·Computer Methods and Programs in Biomedicine·Choon-Hian GohEinly Lim
Nov 3, 2021·Physical and Engineering Sciences in Medicine· NehaS Tewary

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.