PMID: 8604957Mar 11, 1996Paper

An analysis of bacteremias during dental extractions. A double-blind, placebo-controlled study of chlorhexidine

Archives of Internal Medicine
Peter B Lockhart

Abstract

The literature is unclear concerning the nature and incidence of bacteremias from oral surgical procedures, the relationship of these bacteremias to dental disease, and the preventive benefit of antibacterial mouth rinses. To determine the incidence and nature of bacteremias during single-tooth extractions in adults. A double-blind, randomized placebo-controlled study of 70 patients in which the status of dental disease was compared with the incidence and nature of aerobic and anaerobic bacteremias following a single-tooth extraction and the antibacterial effect of rinses with chlorhexidine hydrochloride. Multiple indicators of dental disease were evaluated and recorded before the surgical procedure. Timing of the mouth rinses, the steps in the surgical procedure, and the two blood drawings were controlled for. Thirty-one (94%) of 34 control patients and 62 (89%) of 70 patients overall had blood cultures positive for organisms at either the 1-minute and or 3-minute mark following the initiation of surgery. The majority of cultures yielded gram-positive cocci. Cultures yielded polymicrobial organisms in 17 patients (24%). Although there was a wide range of severity of odontogenic disease, this did not correlate with results of b...Continue Reading

Citations

Dec 1, 1999·Infectious Disease Clinics of North America·P B Lockhart, D T Durack
Apr 10, 2013·Asian Pacific Journal of Tropical Biomedicine·C Ramu, T V Padmanabhan
Jul 12, 2008·British Dental Journal·I TomásP Diz
Aug 29, 2006·British Dental Journal·J L GibbsN Brooks
Jul 27, 2002·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Inmaculada Tomás CarmonaCrispian Scully
May 29, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter B LockhartLarry J Strausbaugh
Jun 11, 2008·Circulation·Peter B LockhartFarah K Bahrani-Mougeot
Jul 28, 2012·Cardiovascular Journal of Africa·Breminand Maharaj, Ahmed C Vayej
Jul 28, 2012·Cardiovascular Journal of Africa·Breminand MaharajAhmed C Vayej
Oct 31, 2012·Cardiovascular Journal of Africa·Breminand MaharajAhmed C Vayej
Feb 21, 2014·Journal of Indian Society of Periodontology·Alka S WaghmareHiroj S Bagde
Apr 2, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Din LamBenjamin Archer
Jul 22, 2010·Journal of Dentistry·Daniel H Fine
Dec 23, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Peter B LockhartJoseph W Cook
Jul 16, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Farah K Bahrani-MougeotPeter B Lockhart
Apr 12, 2008·Annales de cardiologie et d'angéiologie·X Duval
Jun 22, 2005·Journal of Clinical Periodontology·Denis F KinaneBarbara Shearer
Jun 11, 2004·Nephrology·Darryl C Tong, Robert J Walker
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Apr 12, 2008·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Grace Hsiao WuSook-Bin Woo
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May 23, 2015·British Dental Journal·Stephen Hancocks
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Jan 2, 2007·The Journal of the American Dental Association·Michael T BrennanPeter B Lockhart
Nov 20, 2012·Orthopaedics & Traumatology, Surgery & Research : OTSR·L LegoutE Senneville

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