An Analysis of Psychoactive Medications Initiated in the ICU but Continued Beyond Discharge: A Pilot Study of Stewardship.

Journal of Pharmacy Practice
Nicole Lynn KovacicGilles L Fraser

Abstract

Psychoactive medications (PM) are frequently administered in the intensive care unit (ICU) to provide comfort. Interventions focused on preventing their continuation after the acute phase of illness are needed. To determine the frequency that patients with ICU-initiated PM are continued upon ICU and hospital discharge. This single-center, prospective, observational study assessed consecutive adult ICU patients who received scheduled PM. Frequency of PM continued at ICU and hospital discharge was recorded. The patient's primary treatment team was contacted by the pharmacist within 72 hours of ICU discharge to establish rationale for continued use or to suggest discontinuation. Of the 60 patients included, 72% were continued on PM at ICU discharge and 30% at hospital discharge. The pharmacist contacted 40% of treatment teams after ICU discharge and intervention resulted in PM discontinued in 50% of patients. Post ICU discharge, the indication of 41% of patients' PM was unknown by the non-ICU care team or incorrect. Medical ICU patients or those transferred to an outside facility were more likely remain on PM at hospital discharge. PM are frequently continued during transitions of care and often without knowledge of the initial in...Continue Reading

References

Jan 18, 1996·The New England Journal of Medicine·M J Brodie, M A Dichter
Nov 12, 2005·Intensive Care Medicine·Ingrid EgerodLena Johansen
Aug 22, 2006·Critical Care : the Official Journal of the Critical Care Forum·Margaret A PisaniSharon K Inouye
May 24, 2008·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Wesley R Zemrak, George A Kenna
Jan 16, 2009·The New England Journal of Medicine·Wayne A RayC Michael Stein
Jul 7, 2009·Critical Care Clinics·Sangeeta MehtaLisa Burry
Jan 20, 2010·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Didier MeulendijksToine C G Egberts
Nov 28, 2012·Journal of Pharmacy Practice·Karalea D JasiakYvonne C Huckleberry
Jul 6, 2014·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Ruth S BurkCurtis N Sessler
Sep 3, 2014·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Ruth S BurkCurtis N Sessler
Jan 13, 2015·JAMA Internal Medicine·Lisa-Ann FraserAmit X Garg
Apr 19, 2015·Journal of Critical Care·Bridgette L KramKelli R Brooks
Aug 19, 2015·Intensive Care Medicine·Jozef Kesecioglu, Philippe Eggimann
Sep 19, 2015·Journal of Critical Care·A Shaun RoweVictoria W Reynolds
Nov 20, 2015·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Rachel W FlurieMangla Gulati
Jan 29, 2016·Journal of Critical Care·John MarshallJennifer P Stevens
Apr 12, 2016·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Kah Poh LohTara Lagu
May 1, 2016·Journal of Pharmacy Practice·Salia FarrokhMargaret A Pisani
Oct 4, 2016·Journal of Critical Care·David J GagnonGilles L Fraser
Nov 25, 2016·Critical Care : the Official Journal of the Critical Care Forum·Jason E TomichekTimothy D Girard
Jan 5, 2017·Journal of Intensive Care Medicine·Ryan G D'AngeloJeffrey P Gonzales
Jan 21, 2017·Journal of Intensive Care Medicine·Brian GilbertJason A Ferreira
Feb 20, 2018·The Annals of Pharmacotherapy·Joanna L StollingsCarla M Sevin
Oct 23, 2018·The New England Journal of Medicine·Timothy D GirardUNKNOWN MIND-USA Investigators

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

R
ICU
CAM
SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine
K J FarleyTim M Crozier
American Journal of Pharmacy and the Sciences Supporting Public Health
L L Terry
American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Rachel W FlurieMangla S Gulati
© 2022 Meta ULC. All rights reserved