An analysis of side-chain conformation in proteins

International Journal of Peptide and Protein Research
T N BhatM Vijayan

Abstract

The crystal structures of a number of globular proteins are currently available. An analysis of the distribution of side-chains among different allowed conformations in these proteins has been carried out. The observed conformations of individual residues are discussed on the basis of well-known stereochemical criteria. The population distribution of side-chains in different allowed regions in conformational space can be explained largely on the basis of simple steric considerations. In addition to examining the conformational behaviour of individual residues, some population distributions of conformational angles of general interest involving groups of residues have also been analyzed.

References

Sep 5, 1973·Biochemical and Biophysical Research Communications·F R SalemmeJ Kraut
Sep 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·G M EdelmanJ L Wang
Mar 5, 1973·Journal of Molecular Biology·W A HendricksonJ Karle
Jul 2, 1973·Biochemical and Biophysical Research Communications·M J AdamsM G Rossmann
Feb 5, 1974·Journal of Molecular Biology·M BuehnerM G Rossmann
Jan 25, 1974·Journal of Molecular Biology·R Diamond
Oct 15, 1971·Biochemical and Biophysical Research Communications·R A AldenC S Wright

❮ Previous
Next ❯

Citations

Jun 1, 1991·Journal of Biomolecular Structure & Dynamics·P TufferyR Lavery
Mar 15, 1988·European Journal of Biochemistry·T BlundellM Sutcliffe
Dec 1, 1987·International Journal of Peptide and Protein Research·S Clarke
Jan 1, 1980·International Journal of Peptide and Protein Research·C Renneboog-Squilbin
Mar 1, 1995·Nature Structural Biology·E T BaldwinJ W Erickson
Apr 1, 1994·Journal of Protein Chemistry·A Nayeem, H A Scheraga
Sep 1, 1993·International Journal of Peptide and Protein Research·C SudarsanakumarB Varghese
Jun 8, 2007·Proteins·Gevorg GrigoryanAmy E Keating
Mar 1, 2012·BMC Bioinformatics·Md Shariful Islam Bhuyan, Xin Gao
May 1, 1993·International Journal of Peptide and Protein Research·D S JoisM Vijayan
Mar 2, 2011·Environmental Science and Pollution Research International·Khalid Rehman HakeemMunir Ozturk
Mar 1, 1994·International Journal of Peptide and Protein Research·P Chakrabarti
Aug 1, 1983·International Journal of Peptide and Protein Research·D M Salunke, M Vijayan
Jan 1, 1994·Critical Reviews in Biochemistry and Molecular Biology·M S JohnsonT L Blundell
Sep 1, 1996·International Journal of Peptide and Protein Research·S DattaP Balaram
May 1, 1994·Nature Structural Biology·R L Dunbrack, M Karplus
Nov 3, 2006·Proteins·Maxim V Shapovalov, Roland L Dunbrack
Jul 1, 1983·International Journal of Peptide and Protein Research·E BenedettiH A Scheraga
Aug 1, 1997·Protein Science : a Publication of the Protein Society·R L Dunbrack, F E Cohen
Dec 15, 2010·Interdisciplinary Sciences, Computational Life Sciences·Nagasuma ChandraKalidas Yeturu
Mar 4, 2015·Acta Crystallographica. Section C, Structural Chemistry·Sumesh Nicholas
Nov 1, 1993·Protein Science : a Publication of the Protein Society·T P FloresJ M Thornton
Mar 5, 2004·Proteins·Robert J Petrella, Martin Karplus
Jun 8, 2001·Progress in Biophysics and Molecular Biology·P Chakrabarti, D Pal
Jan 1, 1981·Biopolymers·Hans Jäckle, Pier Luigi Luisi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.